{"id":"W2129812133","doi":"10.1261/rna.032268.112","title":"Evidence for a cytoplasmic microprocessor of pri-miRNAs","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Johns Hopkins University; National Institutes of Health; Cleveland Clinic; McGill University; Army Research Laboratory; Army Research Office; University of California, San Francisco; Burroughs Wellcome Fund","keywords":"Drosha; Biology; microRNA; Dicer; Ribonuclease III; Gene silencing; Cytoplasm; Argonaute; Genetics; RNA; Cell biology; Computational biology; Gene; RNA interference","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001435541,0.0002033027,0.0001719297,0.0002072632,0.0002251933,0.0005841717,0.0002468188,0.0004552949,0.001937723],"category_scores_gemma":[0.0003555445,0.0001651303,0.0002241503,0.0000976138,0.0003425036,0.0004404732,0.0004716963,0.0005214158,0.001114999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001950445,"about_ca_system_score_gemma":0.0002528057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001163193,"about_ca_topic_score_gemma":0.0001412301,"domain_scores_codex":[0.9998697,0.00001267734,0.000009828141,0.00004411995,0.00003892217,0.00002469628],"domain_scores_gemma":[0.9996216,0.00009001866,0.00006981517,0.00006193191,0.00008623639,0.00007031739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009200507,0.000007231295,0.0006613327,0.00007611719,0.000004052348,0.0003446903,0.0000186577,0.00001674284,0.9965175,0.0008899863,0.00009105884,0.001280582],"study_design_scores_gemma":[0.0000312616,0.000257307,0.02000092,0.00002953163,0.00003402569,0.005441274,0.00008852305,0.001314702,0.9518774,0.001041732,0.01986539,0.0000179787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560288,0.008403894,0.02337707,0.000547761,0.000199557,0.00003809055,0.0008308945,0.000292177,0.01028164],"genre_scores_gemma":[0.9877565,0.001535663,0.007109597,0.0001729453,0.00006575973,0.0000293728,0.000962195,0.00004490047,0.002323234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001937723,"threshold_uncertainty_score":0.006482303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04175681542442135,"score_gpt":0.3114204482257858,"score_spread":0.2696636328013645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}