{"id":"W2129842013","doi":"10.1158/0008-5472.can-11-2967","title":"PGC-1α Promotes the Growth of ErbB2/Neu–Induced Mammary Tumors by Regulating Nutrient Supply","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Cancer Research UK","keywords":"Coactivator; Downregulation and upregulation; Biology; Endocrinology; Regulator; Mitochondrion; Cancer cell; Receptor; Glycolysis; Peroxisome proliferator-activated receptor; Cancer research; Internal medicine; Cell biology; Cancer; Metabolism; Transcription factor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009049571,0.0003441769,0.0001872337,0.0001877659,0.00009431167,0.0001908931,0.0001137579,0.0001902845,0.000948643],"category_scores_gemma":[0.00005526723,0.0001082941,0.000198222,0.0001452466,0.0001724814,0.0001266479,0.0001532279,0.0005158613,0.0002132134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002561583,"about_ca_system_score_gemma":0.0001778346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006285599,"about_ca_topic_score_gemma":0.0009768091,"domain_scores_codex":[0.9999317,0.000009704149,0.000006605479,0.00001771372,0.00001863466,0.00001572587],"domain_scores_gemma":[0.9999516,0.000003724234,0.00001857991,0.000007000222,0.000004999523,0.00001411928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001585849,0.00004512223,0.0002016868,0.0000384013,0.000004169298,0.00002278596,0.00001002406,0.00008783693,0.9983376,0.00004818909,0.00004178671,0.00100372],"study_design_scores_gemma":[0.00003306,0.0004105472,0.00565109,0.00001053521,0.00001617943,0.0001343711,0.00003751126,0.001508435,0.9885334,0.00005657212,0.003604413,0.000003942572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944886,0.001676965,0.001814989,0.0001651333,0.00004062317,0.00003308649,0.0004077223,0.000100475,0.00127234],"genre_scores_gemma":[0.9930468,0.001489505,0.001903933,0.00007641392,0.0000102045,0.00004251315,0.0005951045,0.00002233957,0.002813197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000948643,"threshold_uncertainty_score":0.00317353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07534840771767871,"score_gpt":0.3894688967571994,"score_spread":0.3141204890395207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}