{"id":"W2129884578","doi":"10.1016/s2213-8587(13)70013-5","title":"Efficacy and safety of insulin degludec three times a week versus insulin glargine once a day in insulin-naive patients with type 2 diabetes: results of two phase 3, 26 week, randomised, open-label, treat-to-target, non-inferiority trials","year":2013,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes Management and Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Insulin degludec; Insulin glargine; Insulin; Internal medicine; Diabetes mellitus; Type 2 diabetes; Metformin; Hypoglycemia; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003180252,0.001846085,0.004107951,0.0006320929,0.0003786437,0.001786177,0.001075563,0.002559355,0.003714991],"category_scores_gemma":[0.003401295,0.001023295,0.00385753,0.0007216088,0.001584576,0.002071167,0.0004434302,0.004134791,0.0007814934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009426892,"about_ca_system_score_gemma":0.0006987526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000704687,"about_ca_topic_score_gemma":0.001130961,"domain_scores_codex":[0.998482,0.0008799668,0.0001253077,0.0002301796,0.0001173154,0.0001651796],"domain_scores_gemma":[0.9980649,0.0008396577,0.0004810631,0.000179547,0.00007499466,0.0003598576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9818647,0.003165216,0.0003489483,0.0003858471,0.0007743664,0.0000191171,0.0000431338,0.0001891689,0.001564305,0.00003198119,0.0001746431,0.01143847],"study_design_scores_gemma":[0.9429689,0.05410245,0.001436898,0.0000320071,0.0004963572,0.00002944611,0.00002882771,0.0002841218,0.0003204785,0.0001057534,0.0001737731,0.00002095917],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876065,0.008305921,0.0006052938,0.0004733788,0.0003646921,0.0008653276,0.0004534598,0.00009166991,0.001233685],"genre_scores_gemma":[0.9904122,0.003762246,0.001483414,0.0009839335,0.0003431283,0.0009210558,0.0005530959,0.00003842143,0.001502567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004107951,"threshold_uncertainty_score":0.016819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06192950866681248,"score_gpt":0.350071599731984,"score_spread":0.2881420910651715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}