{"id":"W2129937169","doi":"10.1002/jgm.834","title":"Comparative analysis of antitumor activity of CD40L, RANKL, and 4‐1BBL <i>in vivo</i> following intratumoral administration of viral vectors or transduced dendritic cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; U.S. Department of Defense","keywords":"RANKL; CD80; CD86; CD40; Tumor necrosis factor alpha; Viral vector; Cancer research; Dendritic cell; Immune system; Biology; Molecular biology; Chemistry; Immunology; T cell; Receptor; Recombinant DNA; In vitro; Cytotoxic T cell; Activator (genetics); Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083591,0.0001408087,0.001052108,0.0003871231,0.00004599538,0.000001990908,0.0001813703,0.00007320899,0.0001613412],"category_scores_gemma":[0.00005394745,0.00008104061,0.0001706564,0.0004390009,0.0004364619,0.0001187689,0.000009742143,0.0002341588,2.85485e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002153614,"about_ca_system_score_gemma":0.000132577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000861127,"about_ca_topic_score_gemma":0.000111498,"domain_scores_codex":[0.9982803,0.000600278,0.0008053413,0.00007844608,0.00008680992,0.0001487843],"domain_scores_gemma":[0.9985369,0.0005422198,0.0006567758,0.0001498177,0.00009930433,0.00001500377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01030491,0.0002273614,0.0004641475,0.00002508473,0.001550631,0.000006721281,0.005287331,0.00008676173,0.981222,0.000007083255,0.00003915091,0.0007788547],"study_design_scores_gemma":[0.003187478,0.002363701,0.01594502,0.0001600689,0.001204265,0.0001040431,0.001394262,0.00003303076,0.9754327,0.000004214774,0.0001030955,0.00006814011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901724,0.008913997,0.0002539385,0.0002828179,0.0002082653,0.0001209902,0.00001565443,0.000001950355,0.00002999891],"genre_scores_gemma":[0.9990085,0.0007895384,0.00005991767,0.00003017151,0.00002427618,6.517831e-7,0.000002927875,0.000005136242,0.00007881669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01548088,"threshold_uncertainty_score":0.330474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909694733530397,"score_gpt":0.2935132679821121,"score_spread":0.2744163206468082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}