{"id":"W2129937169","doi":"10.1002/jgm.834","title":"Comparative analysis of antitumor activity of CD40L, RANKL, and 4‐1BBL <i>in vivo</i> following intratumoral administration of viral vectors or transduced dendritic cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; U.S. Department of Defense","keywords":"RANKL; CD80; CD86; CD40; Tumor necrosis factor alpha; Viral vector; Cancer research; Dendritic cell; Immune system; Biology; Molecular biology; Chemistry; Immunology; T cell; Receptor; Recombinant DNA; In vitro; Cytotoxic T cell; Activator (genetics); Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002754424,0.0004677969,0.0004351161,0.0003637451,0.000125199,0.0003584648,0.0001692459,0.0003288165,0.0006943312],"category_scores_gemma":[0.0001811749,0.0001289903,0.0002854992,0.0002165403,0.0002893876,0.0002771803,0.0000978536,0.0008062299,0.0002063381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003030994,"about_ca_system_score_gemma":0.0003083287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000599517,"about_ca_topic_score_gemma":0.0005548735,"domain_scores_codex":[0.9997622,0.00004530406,0.00001805431,0.00003354697,0.00005865366,0.00008229027],"domain_scores_gemma":[0.9997322,0.00006541089,0.00005926651,0.00002292021,0.00003167483,0.00008848784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006064475,0.0002362672,0.000128234,0.00004459509,0.00001001232,0.00002791302,0.00002657096,0.0001268391,0.9971493,0.00008442879,0.00002831316,0.001531227],"study_design_scores_gemma":[0.00004498529,0.003392514,0.001374665,0.000003679983,0.00003238946,0.00009441826,0.00001725419,0.0008970128,0.9934806,0.00002717317,0.0006308292,0.000004643734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958126,0.001512961,0.001119514,0.00006664644,0.00004046453,0.00003665605,0.0001963224,0.00005102387,0.001163838],"genre_scores_gemma":[0.9940636,0.001160974,0.001359939,0.00004066526,0.00003569486,0.00006940203,0.0005221002,0.00002039646,0.002727366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006943312,"threshold_uncertainty_score":0.002322793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909694733530397,"score_gpt":0.2935132679821121,"score_spread":0.2744163206468082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}