{"id":"W2129957850","doi":"10.1080/1388020039051742","title":"Anticancer Agents from Unique Natural Products Sources","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Natural product; Bioprospecting; Polyketide; Drug discovery; Identification (biology); Natural Product Research; Biology; Computational biology; Biotechnology; Antimitotic Agent; Biochemistry; Gene; Biological activity; In vitro; Genetics; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004073943,0.0004497553,0.0004181478,0.001526725,0.0003592495,0.000623282,0.0003685886,0.0004139194,0.005496524],"category_scores_gemma":[0.0002965785,0.0001879187,0.0004520803,0.000848434,0.0002301848,0.0005372769,0.001086042,0.0009717881,0.001762849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005372615,"about_ca_system_score_gemma":0.000542255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004216207,"about_ca_topic_score_gemma":0.001667299,"domain_scores_codex":[0.9997506,0.00003038544,0.00001899683,0.00004297741,0.0001115476,0.0000455487],"domain_scores_gemma":[0.999792,0.00001877665,0.00003435425,0.00003374525,0.00006299399,0.0000581295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004108196,0.0002437254,0.001845615,0.001768337,0.0001290354,0.001391848,0.0001243843,0.0006009026,0.7107442,0.01247219,0.0108026,0.2594663],"study_design_scores_gemma":[0.0001718661,0.001241062,0.004586779,0.0002950809,0.0001455265,0.002954167,0.00007827303,0.0004199857,0.4076738,0.001900993,0.5804856,0.00004693532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4290464,0.2727216,0.03499399,0.005167132,0.003200342,0.000924709,0.008240816,0.001174686,0.2445305],"genre_scores_gemma":[0.8071303,0.09992523,0.02618869,0.002106732,0.000686839,0.0003651927,0.008511626,0.0001165748,0.05496886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005496524,"threshold_uncertainty_score":0.01838773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0514898743166269,"score_gpt":0.3556712732837359,"score_spread":0.3041813989671091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}