{"id":"W2129957850","doi":"10.1080/1388020039051742","title":"Anticancer Agents from Unique Natural Products Sources","year":2003,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Natural product; Bioprospecting; Polyketide; Drug discovery; Identification (biology); Natural Product Research; Biology; Computational biology; Biotechnology; Antimitotic Agent; Biochemistry; Gene; Biological activity; In vitro; Genetics; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002054291,0.0001878547,0.0003235562,0.0000544004,0.00007420913,0.00001182136,0.0001062401,0.000141859,0.001439468],"category_scores_gemma":[0.0007475149,0.0001239864,0.00007242969,0.0002065124,0.0002777121,0.00003894834,0.00004410037,0.0004210877,0.0001868728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004050709,"about_ca_system_score_gemma":0.00007178433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003535718,"about_ca_topic_score_gemma":0.00000177542,"domain_scores_codex":[0.9985953,0.0001802457,0.0002245492,0.0005013717,0.00009034941,0.0004081645],"domain_scores_gemma":[0.9993494,0.000112413,0.00004609926,0.0002341563,0.0001092604,0.0001486936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002103228,0.0001416476,0.005381942,0.00003526453,0.0001263094,0.00002163481,0.00003958658,6.762552e-8,0.9791207,0.002208079,0.003652713,0.00906169],"study_design_scores_gemma":[0.0005341403,0.00005091669,0.001389046,0.00001517382,0.00009005215,0.00003032649,0.00001015021,0.00002236801,0.6522579,0.0003070278,0.3451663,0.0001266221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789985,0.00474339,0.00001459524,0.0124986,0.0009577902,0.0003909996,0.00002986269,0.00008888102,0.002277333],"genre_scores_gemma":[0.9912477,0.0004770264,0.001300879,0.005835071,0.0004785229,0.000001816692,0.00005125277,0.0000162661,0.0005914874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3415136,"threshold_uncertainty_score":0.9994733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0514898743166269,"score_gpt":0.3556712732837359,"score_spread":0.3041813989671091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}