{"id":"W2130044431","doi":"10.1093/jac/dku058","title":"Has the time come to abandon efavirenz for first-line antiretroviral therapy?","year":2014,"lang":"en","type":"review","venue":"Journal of Antimicrobial Chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Efavirenz; Antiretroviral therapy; Medicine; Human immunodeficiency virus (HIV); Virology; First line therapy; Intensive care medicine; Internal medicine; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007872214,0.000723689,0.003347318,0.0004167474,0.0002596136,0.0001473847,0.0005293433,0.0003396452,0.0001885169],"category_scores_gemma":[0.0000599245,0.0003856398,0.001924576,0.0003864896,0.0001207768,0.0000802927,0.00003660571,0.000532096,0.0001471546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002378133,"about_ca_system_score_gemma":0.0006898097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003296513,"about_ca_topic_score_gemma":0.000002096359,"domain_scores_codex":[0.9971825,0.000106149,0.001459555,0.0003556423,0.0004041924,0.0004919369],"domain_scores_gemma":[0.9974663,0.0003545567,0.001179305,0.0004629463,0.0003047276,0.0002322177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001204516,0.0005960139,0.0000404087,0.002553889,0.002326575,0.00004797327,0.0003596602,0.000001413364,0.0002434837,0.0000069568,0.2292451,0.763374],"study_design_scores_gemma":[0.005894286,0.001349856,0.000007543853,0.007999775,0.0009023133,0.000644994,0.000002404946,0.000004480694,0.0006639416,0.000008086814,0.982144,0.0003783047],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001874255,0.9682748,0.0006112516,0.02415628,0.0008755527,0.003896552,0.00008559445,0.00005160516,0.0001741088],"genre_scores_gemma":[0.000120672,0.9843991,0.00213734,0.002796518,0.001864325,0.0000275162,0.00009514649,0.0001800207,0.008379408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7629957,"threshold_uncertainty_score":0.9998596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04097059359567962,"score_gpt":0.3233344156027699,"score_spread":0.2823638220070903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}