{"id":"W2130183664","doi":"10.1093/brain/awl282","title":"Endurance training and detraining in mitochondrial myopathies due to single large-scale mtDNA deletions","year":2006,"lang":"en","type":"article","venue":"Brain","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Wellcome Trust","keywords":"Heteroplasmy; Mitochondrial DNA; Endurance training; Mitochondrial myopathy; Medicine; Population; Exercise intolerance; Quality of life (healthcare); Physical therapy; Physical medicine and rehabilitation; Training effect; VO2 max; Internal medicine; Biology; Training (meteorology); Genetics; Heart rate; Heart failure; Blood pressure; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804049,0.0001430855,0.0001776774,0.00009993949,0.000096815,0.00002841615,0.00008347586,0.0001660576,0.00002975458],"category_scores_gemma":[0.0002397579,0.0001508146,0.00004944227,0.0001525624,0.00005105135,0.000005299381,0.00005454783,0.0001041448,0.0000106439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001079775,"about_ca_system_score_gemma":0.00003490606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002777136,"about_ca_topic_score_gemma":0.002323504,"domain_scores_codex":[0.9988843,0.0001007316,0.0002268387,0.0003896047,0.00007590114,0.000322686],"domain_scores_gemma":[0.9996361,0.00004067714,0.00004166687,0.0001762902,0.00002826086,0.00007703919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006018204,0.00005703279,0.0007841018,0.000005585602,0.000003915866,0.00001216579,0.0006872946,0.00009413398,0.9892719,0.0003175577,0.00627811,0.002427977],"study_design_scores_gemma":[0.004602932,0.0008702407,0.03201253,0.00009660083,0.00002035538,0.0003531252,0.002682832,0.000280119,0.1710596,0.001072944,0.785915,0.001033736],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9555849,0.0002703356,0.03842507,0.001036577,0.0006183046,0.0002314436,0.00004324463,0.00002711596,0.003762956],"genre_scores_gemma":[0.983318,0.000005671953,0.0118824,0.001709812,0.001179378,0.00006127854,0.000123418,0.00002764716,0.001692371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8182124,"threshold_uncertainty_score":0.6150042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334057600887558,"score_gpt":0.235221557798073,"score_spread":0.2218809817891974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}