{"id":"W2130190017","doi":"10.1016/s1474-4422(12)70225-9","title":"Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial","year":2012,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":399,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; McMaster University; Queen Elizabeth II Health Sciences Centre; London Health Sciences Centre; University of Toronto; Royal University Hospital; Western University; St. Michael's Hospital; University of Saskatchewan; Université Laval; Toronto Western Hospital; Ottawa Hospital; University of Alberta Hospital; University Health Network; Dalhousie University; Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Medicine; Aneurysm; Adverse effect; Placebo; Stroke (engine); Clinical trial; Population; Randomized controlled trial; Double blind; Anesthesia; Internal medicine; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001428895,0.001489589,0.004152486,0.0003995809,0.0005290587,0.00143338,0.001070765,0.002448824,0.004110351],"category_scores_gemma":[0.002224106,0.0007965842,0.002062312,0.0004133051,0.001366368,0.001633482,0.0003974873,0.003227779,0.0007647123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004938323,"about_ca_system_score_gemma":0.0009706593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007020105,"about_ca_topic_score_gemma":0.001253739,"domain_scores_codex":[0.9994343,0.0002817076,0.00005961443,0.0001059591,0.00004572994,0.00007264002],"domain_scores_gemma":[0.9989826,0.0003337658,0.0002860991,0.00008194851,0.00007563675,0.0002400423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9860398,0.002017541,0.000524406,0.0008848838,0.001167934,0.00003499855,0.00005045543,0.0001328685,0.001046432,0.00008215915,0.0004052435,0.007613422],"study_design_scores_gemma":[0.9622207,0.03386894,0.001763877,0.00005895098,0.0008192844,0.00004116639,0.0000264091,0.0002533673,0.0002635824,0.000144694,0.0005207194,0.00001846475],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974133,0.01835005,0.0007803285,0.0009030271,0.00113899,0.001560002,0.0007814403,0.0001041998,0.002248965],"genre_scores_gemma":[0.9817405,0.008671272,0.001394059,0.0013018,0.001103656,0.002042,0.001042137,0.00002457787,0.002680182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004152486,"threshold_uncertainty_score":0.01375055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673006632297909,"score_gpt":0.2665545161590198,"score_spread":0.2498244498360407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}