{"id":"W2130253216","doi":"10.1124/jpet.108.150144","title":"HIV-1 Tat Protein-Induced Rapid and Reversible Decrease in [3H]Dopamine Uptake: Dissociation of [3H]Dopamine Uptake and [3H]2β-Carbomethoxy-3-β-(4-fluorophenyl)tropane (WIN 35,428) Binding in Rat Striatal Synaptosomes","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; National Institutes of Health; York University; University of South Carolina","keywords":"Dopamine Uptake Inhibitors; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine transporter; Chemistry; Tropane; Reuptake; Pharmacology; Biochemistry; Biology; Endocrinology; Stereochemistry; Serotonin; Receptor; Dopaminergic","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001931609,0.0004877583,0.000460182,0.0003099461,0.000311586,0.0003845177,0.0006187903,0.0004194853,0.002120906],"category_scores_gemma":[0.0002862555,0.000442804,0.000492093,0.0003622555,0.0004531898,0.0004942686,0.0002507719,0.001612934,0.0005695079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009915691,"about_ca_system_score_gemma":0.0006555098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005353108,"about_ca_topic_score_gemma":0.008404914,"domain_scores_codex":[0.9997961,0.00002175188,0.00001536108,0.00003121152,0.00003975988,0.00009575796],"domain_scores_gemma":[0.9998098,0.000046806,0.00003168448,0.00003506296,0.00002098887,0.00005566519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001022723,0.0001058368,0.0001966558,0.00007673211,0.00003391896,0.0001967567,0.0000749331,0.00006476935,0.9965641,0.0002902891,0.00009659978,0.001276611],"study_design_scores_gemma":[0.00004881955,0.0004182357,0.007854501,0.000009119209,0.000029814,0.0002996081,0.00007282441,0.0005434346,0.9901062,0.00007943784,0.0005258528,0.00001206229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941309,0.001844146,0.001128562,0.0001161763,0.00004961799,0.00003623368,0.0008703758,0.00009850341,0.001725445],"genre_scores_gemma":[0.9916103,0.001039589,0.001376739,0.00007065218,0.0000151349,0.00006524489,0.001311132,0.00004041766,0.004470831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005353108,"threshold_uncertainty_score":0.01064384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02763235015703823,"score_gpt":0.3210754397117309,"score_spread":0.2934430895546927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}