{"id":"W2130253216","doi":"10.1124/jpet.108.150144","title":"HIV-1 Tat Protein-Induced Rapid and Reversible Decrease in [3H]Dopamine Uptake: Dissociation of [3H]Dopamine Uptake and [3H]2β-Carbomethoxy-3-β-(4-fluorophenyl)tropane (WIN 35,428) Binding in Rat Striatal Synaptosomes","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; National Institutes of Health; York University; University of South Carolina","keywords":"Dopamine Uptake Inhibitors; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine transporter; Chemistry; Tropane; Reuptake; Pharmacology; Biochemistry; Biology; Endocrinology; Stereochemistry; Serotonin; Receptor; Dopaminergic","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007366516,0.0003048325,0.0006893473,0.0004689664,0.0001463773,0.00002214405,0.0001505741,0.0002648228,0.0002167633],"category_scores_gemma":[0.0000451595,0.0002600967,0.00008411658,0.000242571,0.0002669083,0.0002710355,0.00007710357,0.0005817727,0.000005235605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002175157,"about_ca_system_score_gemma":0.0001435757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002545429,"about_ca_topic_score_gemma":0.000005532841,"domain_scores_codex":[0.9977612,0.0005844244,0.0007540859,0.0002960752,0.0001154255,0.0004887803],"domain_scores_gemma":[0.9990928,0.0002094614,0.0004224681,0.00008579141,0.00006562281,0.0001238127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003277521,0.001074484,0.004127926,0.00002378319,0.0004138827,0.0001317163,0.00105747,0.000002253742,0.9775819,0.00003903735,0.00008275226,0.01218724],"study_design_scores_gemma":[0.01555351,0.00346192,0.01016,0.00009069058,0.0001581216,0.0002181306,0.001912568,0.0000232163,0.9669935,0.00005717956,0.001129531,0.000241708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.971695,0.02665983,0.000006284934,0.0007726633,0.0002248391,0.0005416509,0.00005268496,0.000009300999,0.00003773054],"genre_scores_gemma":[0.9964089,0.002748732,0.0003582781,0.0001571494,0.0000630782,0.00001720802,0.00004570284,0.00001704348,0.0001839476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02471384,"threshold_uncertainty_score":0.9999851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02763235015703823,"score_gpt":0.3210754397117309,"score_spread":0.2934430895546927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}