{"id":"W2130290558","doi":"10.1128/aac.00380-10","title":"Depolarization, Bacterial Membrane Composition, and the Antimicrobial Action of Ceragenins","year":2010,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Antimicrobial; Depolarization; Chemistry; Membrane; Microbiology; Biology; Biophysics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002285742,0.0003631917,0.0002684212,0.0001748493,0.0001529367,0.0004166607,0.0002002625,0.0005637197,0.0004311993],"category_scores_gemma":[0.000434477,0.0001825493,0.0002106606,0.0001508568,0.0004164913,0.0006034019,0.0003164173,0.0006855116,0.0002416884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003418951,"about_ca_system_score_gemma":0.0003591439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004341241,"about_ca_topic_score_gemma":0.0003587654,"domain_scores_codex":[0.9997625,0.00005738327,0.00002200522,0.00003530786,0.00007796343,0.00004479635],"domain_scores_gemma":[0.9997059,0.00006457651,0.0000995943,0.00001924306,0.00005473538,0.00005596418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000666031,0.000007851029,0.0002897607,0.00002083291,0.000002066999,0.00003830838,0.000008185047,0.00003246582,0.9990295,0.00007983056,0.000004792981,0.0004198899],"study_design_scores_gemma":[0.000008106404,0.0001155758,0.007692855,0.000007874294,0.000005138023,0.0002140001,0.00004214149,0.0005256748,0.990628,0.0001021245,0.0006531142,0.000005290944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905945,0.002937187,0.004277113,0.0002207076,0.00002223953,0.00002768469,0.0001608077,0.0000329976,0.001726799],"genre_scores_gemma":[0.9964622,0.0009456341,0.00179277,0.00009274593,0.000007179323,0.00002366759,0.0001715141,0.000007946999,0.0004963616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005637197,"threshold_uncertainty_score":0.002480626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008346161941142316,"score_gpt":0.2246389260914944,"score_spread":0.216292764150352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}