{"id":"W2130343873","doi":"10.1016/j.vaccine.2012.06.011","title":"Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Respiratory viral infections research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Alberta; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Krembil Foundation; Canada Research Chairs","keywords":"CpG Oligodeoxynucleotide; Immunogenicity; Virus; Immune system; Virology; Mononegavirales; Vaccination; Adjuvant; Biology; Antibody; Innate immune system; Immunology; Paramyxoviridae; Viral disease; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002790614,0.000521719,0.000292233,0.0002011579,0.0001237579,0.0002361953,0.0002340414,0.0006552481,0.0006149728],"category_scores_gemma":[0.000202151,0.0002347058,0.000323807,0.00008871251,0.0002605444,0.000311712,0.0002519851,0.0006834366,0.0001989114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646612,"about_ca_system_score_gemma":0.000212695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003048887,"about_ca_topic_score_gemma":0.0003039475,"domain_scores_codex":[0.999818,0.00003588791,0.00001522912,0.000037269,0.00003633359,0.0000572248],"domain_scores_gemma":[0.9999082,0.00002527243,0.00002508688,0.000008755215,0.00001272402,0.00001997102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003707185,0.0000823384,0.00008731831,0.00003781599,0.000007546395,0.0000327163,0.00001289593,0.0001755583,0.9980201,0.0000679335,0.00002459023,0.001080593],"study_design_scores_gemma":[0.0001055965,0.002440295,0.001681683,0.000006650559,0.00003649452,0.0001622496,0.00001345917,0.001488208,0.9933362,0.00006058802,0.0006620033,0.000006491965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973373,0.000658902,0.001425079,0.0000439621,0.00004711644,0.00003857929,0.00005971785,0.00002261249,0.0003667221],"genre_scores_gemma":[0.9979297,0.0002459351,0.0008871698,0.00003918943,0.00001591353,0.000029126,0.0001158808,0.000005878754,0.0007311226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006552481,"threshold_uncertainty_score":0.002057254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617583762231897,"score_gpt":0.2772360781077757,"score_spread":0.2610602404854567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}