{"id":"W2130356495","doi":"10.1101/cshperspect.a009365","title":"Programmed Cell Death in Parkinson's Disease","year":2012,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":244,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Programmed cell death; Autophagy; Parkin; Mitophagy; PINK1; Cell biology; Biology; Caspase; Apoptosis; Necroptosis; Neurodegeneration; Neuroscience; Parkinson's disease; Disease; Medicine; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007310973,0.0005430555,0.001504831,0.0006928161,0.00008444305,0.00004099981,0.0006283448,0.0001943947,0.0002542431],"category_scores_gemma":[0.0008419888,0.0004373069,0.0002212568,0.0009302595,0.0002748546,0.00013579,0.0001708431,0.001075654,0.00007530325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006630754,"about_ca_system_score_gemma":0.0001763474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008395145,"about_ca_topic_score_gemma":0.000007014113,"domain_scores_codex":[0.9966285,0.0004310327,0.000641065,0.001017128,0.0004939126,0.0007883438],"domain_scores_gemma":[0.9983138,0.0004154624,0.0002895206,0.0005615794,0.00002719352,0.0003923884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004826498,0.008529129,0.01793176,0.09052177,0.0001587249,0.006215672,0.01568223,0.00003793386,0.005794718,0.1930423,0.0004556288,0.6611475],"study_design_scores_gemma":[0.0005729427,0.00006093602,0.0006703385,0.01049297,0.0001672261,0.000001194147,0.0001332907,0.00003938983,0.00004065022,0.00001487891,0.9873376,0.0004685864],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00112047,0.9956053,0.00001916051,0.00008145928,0.0005656077,0.001380493,0.000005935442,0.0001005832,0.001120912],"genre_scores_gemma":[0.06977747,0.9288547,0.0001469416,0.00005802196,0.000688017,0.0002151934,7.517119e-7,0.0001214735,0.0001374365],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.986882,"threshold_uncertainty_score":0.9998079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08719313476537346,"score_gpt":0.3352974911650174,"score_spread":0.248104356399644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}