{"id":"W2130356495","doi":"10.1101/cshperspect.a009365","title":"Programmed Cell Death in Parkinson's Disease","year":2012,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Medicine","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":244,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Programmed cell death; Autophagy; Parkin; Mitophagy; PINK1; Cell biology; Biology; Caspase; Apoptosis; Necroptosis; Neurodegeneration; Neuroscience; Parkinson's disease; Disease; Medicine; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040236,0.000999484,0.001237255,0.001791736,0.0003533657,0.0008265155,0.0007383047,0.001098158,0.002392108],"category_scores_gemma":[0.0003457702,0.0002370401,0.00026915,0.001938627,0.000538596,0.001113725,0.0006390178,0.001712819,0.002963092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00069373,"about_ca_system_score_gemma":0.0008894645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008855559,"about_ca_topic_score_gemma":0.001484347,"domain_scores_codex":[0.9998555,0.00002085749,0.00002087568,0.00002489563,0.00006302648,0.00001481598],"domain_scores_gemma":[0.9998528,0.00004707572,0.00002184905,0.000006496291,0.00005087964,0.00002086706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005581449,0.00005478142,0.0001629946,0.008460351,0.00003829279,0.0003178893,0.0000784231,0.0002906456,0.002285385,0.004220971,0.03998616,0.9440483],"study_design_scores_gemma":[0.00001624382,0.00006959948,0.0007242753,0.001862297,0.00003432015,0.002288013,0.00005769031,0.00005920813,0.0003796663,0.002976258,0.9915176,0.00001477643],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009227026,0.9981212,0.0001155272,0.0001839201,0.0002587845,0.000004491808,0.00001019831,0.000008080752,0.001205402],"genre_scores_gemma":[0.0007847461,0.9976315,0.000179499,0.0001933409,0.0001951696,0.000006588449,0.00002524583,0.000001454939,0.0009823974],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002392108,"threshold_uncertainty_score":0.0080024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08719313476537346,"score_gpt":0.3352974911650174,"score_spread":0.248104356399644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}