{"id":"W2130373720","doi":"10.1210/jc.2002-021710","title":"Mechanism of Cortisol/Progesterone Antagonism in the Regulation of 15-Hydroxyprostaglandin Dehydrogenase Activity and Messenger Ribonucleic Acid Levels in Human Chorion and Placental Trophoblast Cells at Term","year":2003,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Institutes of Health Research","funders":"","keywords":"Trophoblast; Mechanism (biology); Antagonism; Cell biology; Internal medicine; Chemistry; Messenger RNA; Endocrinology; Biology; Placenta; Pregnancy; Fetus; Medicine; Receptor; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001878587,0.0003098093,0.0003215729,0.0001972285,0.0001565663,0.0003488903,0.0002141628,0.0002584025,0.00158732],"category_scores_gemma":[0.0002229588,0.0001628996,0.0002695578,0.00009610159,0.0003618778,0.0001291697,0.0001859064,0.0003828369,0.0003449367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004239931,"about_ca_system_score_gemma":0.0003828096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442844,"about_ca_topic_score_gemma":0.001416419,"domain_scores_codex":[0.9998376,0.00004492391,0.00001366951,0.00003588114,0.00003153842,0.00003619386],"domain_scores_gemma":[0.9998758,0.00003295903,0.00002289547,0.00001700796,0.00001406472,0.00003726412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004722546,0.00002052187,0.0003193385,0.00006879241,0.000009689926,0.0002183389,0.00004588689,0.00003427261,0.9952034,0.0001523578,0.00005356123,0.003401592],"study_design_scores_gemma":[0.00008474306,0.001262219,0.03353317,0.00002118696,0.00005125554,0.000752306,0.0001836393,0.0004979681,0.9551884,0.0002363149,0.008177567,0.00001126549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562503,0.03307299,0.002875998,0.0005057494,0.0001986325,0.0001139359,0.0008114022,0.0001887658,0.005982389],"genre_scores_gemma":[0.9888217,0.005011085,0.001526354,0.0001899302,0.0000522359,0.00012063,0.0004710833,0.00001558194,0.003791349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00158732,"threshold_uncertainty_score":0.005310178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01795660266337834,"score_gpt":0.300770741803959,"score_spread":0.2828141391405806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}