{"id":"W2130379010","doi":"10.1093/nar/gkp769","title":"Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Ontario","keywords":"Homing endonuclease; Biology; Endonuclease; Genetics; Gene; Gene conversion; DNA; Intron; Terminator (solar); Plasmid; Restriction enzyme; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001792452,0.0004617907,0.0001819935,0.000260653,0.0001063866,0.0002983018,0.0001906653,0.0001715058,0.001279057],"category_scores_gemma":[0.0001481708,0.0001456813,0.0002805018,0.00008515124,0.0001927157,0.0001420793,0.0004811378,0.0004619063,0.0005532662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001610461,"about_ca_system_score_gemma":0.0001539315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004335846,"about_ca_topic_score_gemma":0.0004528348,"domain_scores_codex":[0.9997702,0.00003920282,0.00001779724,0.00004881643,0.0000702032,0.00005385029],"domain_scores_gemma":[0.9998155,0.00003169657,0.0000534576,0.00002619534,0.00002209138,0.00005102468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002038862,0.00000866109,0.0001070702,0.000009262089,0.000001631121,0.00001355168,0.000007455227,0.000008567806,0.9994925,0.00003154113,0.000006476898,0.0002928231],"study_design_scores_gemma":[0.000004626163,0.0001106907,0.002385408,0.000003204349,0.000005171224,0.000171098,0.00002031804,0.0004247039,0.9956962,0.00002278511,0.001153272,0.000002434529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927492,0.0003600026,0.005526724,0.00003157443,0.00001403297,0.0000148589,0.0001046749,0.00009432428,0.001104531],"genre_scores_gemma":[0.9931253,0.0001945917,0.002694983,0.00001751369,0.000004292025,0.00001161901,0.0004463388,0.00004871646,0.003456624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001279057,"threshold_uncertainty_score":0.004278898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02232578083348763,"score_gpt":0.3440259872759837,"score_spread":0.3217002064424961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}