{"id":"W2130379010","doi":"10.1093/nar/gkp769","title":"Phage T4 mobE promotes trans homing of the defunct homing endonuclease I-TevIII","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Ontario","keywords":"Homing endonuclease; Biology; Endonuclease; Genetics; Gene; Gene conversion; DNA; Intron; Terminator (solar); Plasmid; Restriction enzyme; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006264661,0.0001527603,0.0001640589,0.00007935328,0.0001877323,0.00003422435,0.0005144518,0.0001402,0.00005805304],"category_scores_gemma":[0.00021663,0.0001195059,0.0001548469,0.0002804338,0.0001521243,0.000005599472,0.0001403055,0.0003052313,0.000009462692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002016511,"about_ca_system_score_gemma":0.00007983245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001324756,"about_ca_topic_score_gemma":0.000009691488,"domain_scores_codex":[0.9984298,0.000100533,0.0002282576,0.0003373694,0.0004158149,0.0004882461],"domain_scores_gemma":[0.9990995,0.000030359,0.00003462315,0.0005938787,0.0001302317,0.0001113933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005519558,0.00007502262,0.001580608,0.0000390647,0.0000235549,0.000004568888,0.0002545563,0.0001003081,0.9751707,0.00006681391,0.000606763,0.02202284],"study_design_scores_gemma":[0.0006238024,0.0004170928,0.01970213,0.00005752025,0.00001472148,0.00001733593,0.0001929034,0.0006235705,0.9653512,0.000110311,0.0127194,0.0001700797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930711,0.001279807,0.001577011,0.0003838631,0.00007185487,0.000340835,0.0000112037,0.00001613657,0.003248193],"genre_scores_gemma":[0.9982185,0.0001373972,0.0007250425,0.0000590167,0.0001748976,0.00001036707,0.000007330864,0.00002895631,0.0006384469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02185276,"threshold_uncertainty_score":0.4873309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02232578083348763,"score_gpt":0.3440259872759837,"score_spread":0.3217002064424961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}