{"id":"W2130509253","doi":"10.1065/espr2007.03.402","title":"The OECD Validation Program of the H295R Steroidogenesis Assay for the Identification of In Vitro Inhibitors and Inducers of Testosterone and Estradiol Production. Phase 2: Inter-Laboratory Pre-Validation Studies (8 pp)","year":2007,"lang":"en","type":"article","venue":"Environmental Science and Pollution Research","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Testosterone (patch); Inducer; In vitro; Ecotoxicology; Identification (biology); Chemistry; Endocrinology; Internal medicine; Pharmacology; Biology; Medicine; Environmental chemistry; Biochemistry; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01309282,0.003541408,0.001499928,0.007035128,0.003225816,0.00157741,0.004481742,0.002209736,0.005134172],"category_scores_gemma":[0.007575843,0.001952215,0.002610405,0.003381142,0.001738795,0.0009304357,0.002149519,0.001914058,0.007517341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00253882,"about_ca_system_score_gemma":0.007062331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02026455,"about_ca_topic_score_gemma":0.02842111,"domain_scores_codex":[0.9868368,0.005161663,0.001051585,0.0006234436,0.005826585,0.0004998816],"domain_scores_gemma":[0.9895132,0.00131694,0.0009485953,0.001385713,0.00643244,0.0004031109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002895442,0.004100879,0.01552919,0.002107389,0.0005468084,0.00112312,0.0005985206,0.005247341,0.6223372,0.003841241,0.08318046,0.2584923],"study_design_scores_gemma":[0.0005698484,0.005554765,0.03936815,0.0004092474,0.0005368066,0.001784024,0.0002434005,0.002059141,0.7273374,0.000643859,0.2212991,0.0001942784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2659395,0.03711078,0.4131785,0.006173561,0.005043343,0.02527916,0.1071517,0.00991206,0.1302114],"genre_scores_gemma":[0.2451101,0.0229365,0.3574406,0.003607306,0.0008205717,0.02132422,0.2611348,0.001466571,0.08615945],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02026455,"threshold_uncertainty_score":0.06924224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0339998881269717,"score_gpt":0.4141991611829584,"score_spread":0.3801992730559867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}