{"id":"W2130509253","doi":"10.1065/espr2007.03.402","title":"The OECD Validation Program of the H295R Steroidogenesis Assay for the Identification of In Vitro Inhibitors and Inducers of Testosterone and Estradiol Production. Phase 2: Inter-Laboratory Pre-Validation Studies (8 pp)","year":2007,"lang":"en","type":"article","venue":"Environmental Science and Pollution Research","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Testosterone (patch); Inducer; In vitro; Ecotoxicology; Identification (biology); Chemistry; Endocrinology; Internal medicine; Pharmacology; Biology; Medicine; Environmental chemistry; Biochemistry; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.006288097,0.00007267068,0.0000919089,0.00005643628,0.0004397314,0.00002972026,0.0001804079,0.00002724257,0.000002022637],"category_scores_gemma":[0.000562957,0.00003955049,0.00001702663,0.0003498331,0.00369085,0.0002509287,0.0002067258,0.00009733665,2.909968e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001252237,"about_ca_system_score_gemma":0.00001747688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007639828,"about_ca_topic_score_gemma":0.00001505449,"domain_scores_codex":[0.9985151,0.0001411198,0.0003356812,0.0002446581,0.0005627191,0.0002006674],"domain_scores_gemma":[0.9991947,0.0003576273,0.0001962201,0.0001885486,0.00002495625,0.00003790234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006050466,0.0001164743,0.01307097,0.00002076385,0.000005682471,4.218451e-8,0.0007471988,0.00003229787,0.9047421,0.000007042564,0.0000264212,0.08117048],"study_design_scores_gemma":[0.0002442069,0.0001473645,0.1401523,0.00001832268,0.00000953041,0.000001518524,0.002199443,0.0002347062,0.8567843,0.00004347994,0.0001267259,0.00003814006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976095,0.000640534,0.00001583579,0.0006119871,0.00006225421,0.001033834,0.00001597803,0.000002605282,0.000007449823],"genre_scores_gemma":[0.9992703,0.000535946,0.00008632873,0.000005164396,0.00001671687,0.00005425258,0.000001730593,0.000003859416,0.00002565534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1270813,"threshold_uncertainty_score":0.9990205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0339998881269717,"score_gpt":0.4141991611829584,"score_spread":0.3801992730559867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}