{"id":"W2130570549","doi":"10.1016/s0140-6736(13)60683-2","title":"Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial","year":2013,"lang":"en","type":"article","venue":"The Lancet","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":724,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"Mitsubishi Tanabe Pharma Corporation","keywords":"Glimepiride; Medicine; Canagliflozin; Metformin; Type 2 diabetes; Population; Internal medicine; Randomized controlled trial; Diabetes mellitus; Clinical endpoint; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003681133,0.001859921,0.004532535,0.0004953602,0.000458734,0.001721459,0.00108454,0.002642144,0.006603837],"category_scores_gemma":[0.003643988,0.001065512,0.003639836,0.0005098133,0.001820734,0.001951011,0.0005247314,0.004035417,0.001179715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009662133,"about_ca_system_score_gemma":0.0008750448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009934433,"about_ca_topic_score_gemma":0.001795564,"domain_scores_codex":[0.9989008,0.0005758558,0.00008085873,0.0001937256,0.00008416369,0.0001646161],"domain_scores_gemma":[0.9980059,0.0007784308,0.000439963,0.0002366944,0.00008680223,0.0004522006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9920575,0.001054355,0.0003166368,0.0002592111,0.0008758182,0.00001538441,0.00002557693,0.0001240392,0.0006202896,0.00003279017,0.0002691794,0.004349167],"study_design_scores_gemma":[0.9783162,0.0191726,0.001276755,0.00002164696,0.000648217,0.00001422523,0.00001490546,0.0001952258,0.0001258761,0.00008009737,0.0001227014,0.00001159169],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888703,0.006255006,0.0003980019,0.0009840097,0.0005646184,0.0006841262,0.0006049178,0.0001159483,0.001523006],"genre_scores_gemma":[0.9934735,0.001825241,0.0006350493,0.001016783,0.0004910366,0.0006723295,0.0006232675,0.00002743804,0.001235357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006603837,"threshold_uncertainty_score":0.02209204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03620259462299996,"score_gpt":0.284852838621018,"score_spread":0.248650243998018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}