{"id":"W2130572824","doi":"10.1186/1477-5956-9-6","title":"Factors affecting the accuracy of urine-based biomarkers of BSE","year":2011,"lang":"en","type":"article","venue":"Proteome Science","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"Alberta Prion Research Institute; Public Health Agency; Public Health Agency of Canada","keywords":"Bovine spongiform encephalopathy; Disease; Medicine; Urine; Biology; Pathology; Prion protein; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005681227,0.00007941747,0.0000786437,0.00005108205,0.0001081516,0.000009438969,0.000490984,0.00002999706,0.00003570108],"category_scores_gemma":[0.0008112254,0.00005059665,0.00007315351,0.0003042916,0.0004831306,0.000008273271,0.000139135,0.0000357205,7.195864e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005747493,"about_ca_system_score_gemma":0.0001719214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006507942,"about_ca_topic_score_gemma":0.000002159333,"domain_scores_codex":[0.9992575,0.00003570149,0.0001473001,0.0002043047,0.0001819436,0.0001732663],"domain_scores_gemma":[0.9993048,0.00002606165,0.0001778098,0.0003359137,0.0000973653,0.00005804703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003586992,0.00002817157,0.01488862,0.00003181217,0.000008105462,1.672907e-7,0.0001134371,0.00000900015,0.9812671,0.00002250217,0.000005201279,0.003590037],"study_design_scores_gemma":[0.0001151086,0.0001242955,0.04507484,0.00002144777,0.000005789359,4.159538e-7,0.0001157409,0.00005274088,0.9542933,0.00005644362,0.00007513694,0.00006470572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978773,0.0004200464,0.0009824794,0.00002139641,0.00005031293,0.0003354324,0.000006828078,0.000005026321,0.0003011686],"genre_scores_gemma":[0.9987136,0.00001594872,0.00121288,0.00001996144,0.00001330942,0.00001163718,0.00000145681,0.000004964577,0.000006259586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03018621,"threshold_uncertainty_score":0.2063272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04145227789968175,"score_gpt":0.2809852831326324,"score_spread":0.2395330052329507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}