{"id":"W2130572824","doi":"10.1186/1477-5956-9-6","title":"Factors affecting the accuracy of urine-based biomarkers of BSE","year":2011,"lang":"en","type":"article","venue":"Proteome Science","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"Alberta Prion Research Institute; Public Health Agency; Public Health Agency of Canada","keywords":"Bovine spongiform encephalopathy; Disease; Medicine; Urine; Biology; Pathology; Prion protein; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01144431,0.0007314055,0.0008278161,0.001625904,0.0006286234,0.002215032,0.0006038233,0.001311472,0.0009689314],"category_scores_gemma":[0.03447973,0.0002723321,0.0003910299,0.00115925,0.00103945,0.0006208065,0.0006608929,0.0006458653,0.0006358708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004215599,"about_ca_system_score_gemma":0.000332622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001717392,"about_ca_topic_score_gemma":0.002382996,"domain_scores_codex":[0.9898689,0.003699771,0.001112531,0.001830991,0.002909663,0.0005782286],"domain_scores_gemma":[0.9753744,0.01535228,0.003025513,0.001245708,0.004521266,0.0004807595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002576513,0.0001814175,0.8971555,0.0004141811,0.0006262953,0.0001999547,0.0003115793,0.002009925,0.06106582,0.0002352434,0.0008240321,0.03439955],"study_design_scores_gemma":[0.00003559025,0.001272056,0.8752301,0.0002511531,0.0005337757,0.002006134,0.0004898401,0.02770397,0.08823154,0.0007262208,0.003449507,0.00006997173],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727287,0.008701398,0.01327708,0.0005537143,0.0003192399,0.00009955853,0.001332975,0.0001972841,0.002790069],"genre_scores_gemma":[0.9941766,0.0005164883,0.004269616,0.0001766254,0.00004189551,0.00002650185,0.0005034036,0.00001769343,0.0002710567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01144431,"threshold_uncertainty_score":0.06052405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04145227789968175,"score_gpt":0.2809852831326324,"score_spread":0.2395330052329507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}