{"id":"W2130591775","doi":"10.1186/s12950-014-0030-7","title":"Induction of acute lung inflammation in mice with hemorrhagic shock and resuscitation: role of HMGB1","year":2014,"lang":"en","type":"article","venue":"Journal of Inflammation","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Lawson Health Research Institute; Canadian Armed Forces","funders":"Health Services Research and Development","keywords":"HMGB1; Medicine; Lung; Resuscitation; Lipopolysaccharide; Myeloperoxidase; Inflammation; Shock (circulatory); Organ dysfunction; TLR4; Immunology; Sepsis; Pharmacology; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000442956,0.0008588551,0.000671203,0.000703321,0.0002828187,0.0003695949,0.0003257534,0.0007836904,0.002858636],"category_scores_gemma":[0.0001810359,0.0003567766,0.0006132407,0.0002746431,0.0006427229,0.0005228437,0.0003294412,0.001924513,0.0005627745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003237737,"about_ca_system_score_gemma":0.0003488699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002795636,"about_ca_topic_score_gemma":0.0003759414,"domain_scores_codex":[0.9996799,0.00006877274,0.00004335126,0.00005329215,0.00006514222,0.00008951522],"domain_scores_gemma":[0.9995671,0.00002614513,0.0001829696,0.00003517266,0.00003238045,0.0001560882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004536215,0.0008685275,0.001239701,0.0002851491,0.0000353777,0.0002612882,0.00008528445,0.00009948148,0.9894767,0.0002033925,0.000200946,0.002707887],"study_design_scores_gemma":[0.0005823117,0.01743263,0.02839056,0.0001281797,0.0001524111,0.001210929,0.0003307594,0.001817536,0.9463737,0.0003206533,0.003224839,0.00003542131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888615,0.003560067,0.003567823,0.0007103971,0.0001570365,0.0001811088,0.001171493,0.0002526473,0.001538009],"genre_scores_gemma":[0.9856711,0.002275855,0.005650915,0.0003515465,0.00008695364,0.0005549414,0.00108995,0.00003787978,0.004280922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002858636,"threshold_uncertainty_score":0.009563088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005857005423715047,"score_gpt":0.2624247841290909,"score_spread":0.2565677787053759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}