{"id":"W2130622910","doi":"10.1186/1750-1172-9-68","title":"LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains","year":2014,"lang":"en","type":"article","venue":"Orphanet Journal of Rare Diseases","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for GM Crops; National Center of Neurology and Psychiatry; Ministry of Health, Labour and Welfare; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; University of Tsukuba; International Development Research Centre; National Center for Geriatrics and Gerontology; National Center for Global Health and Medicine","keywords":"Biology; Leukoencephalopathy; Microglia; Pathology; Sequestosome 1; White matter; Myelin; Progressive multifocal leukoencephalopathy; Autophagy; Oligodendrocyte; Central nervous system; Neuroscience; Immunology; Inflammation; Multiple sclerosis; Medicine; Disease; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020324,0.0002765598,0.0003238311,0.0004193683,0.0001475568,0.0001918014,0.0005303351,0.00004909782,0.0006061981],"category_scores_gemma":[0.001365886,0.0002438251,0.0001760523,0.0002867238,0.00006476322,0.0008134469,0.00004795224,0.0002284759,0.00008433183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003682246,"about_ca_system_score_gemma":0.0001390031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001062354,"about_ca_topic_score_gemma":0.000002112899,"domain_scores_codex":[0.9971836,0.000661592,0.0006034875,0.0004426413,0.0007804428,0.0003282009],"domain_scores_gemma":[0.9979641,0.0004071917,0.000418439,0.0004331036,0.00008939514,0.0006877861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002053093,0.001479382,0.002143612,0.0001126061,0.00001161297,0.002081679,0.0003209237,0.002345702,0.9661688,0.01057289,0.005739374,0.006970315],"study_design_scores_gemma":[0.002902663,0.000757446,0.02450815,0.0001746782,0.00004910924,0.000120178,0.00003563428,0.006141713,0.951161,0.003259574,0.01039859,0.0004912379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975365,0.0001125092,0.0001941274,0.0009923638,0.0005319832,0.0001906124,0.0001389458,0.00007180089,0.0002311055],"genre_scores_gemma":[0.9922029,0.0001689257,0.00007300175,0.006756593,0.0003251081,0.000009438271,0.00001036759,0.0000437895,0.0004098729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02236454,"threshold_uncertainty_score":0.9942897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02301688210739175,"score_gpt":0.2655011569062408,"score_spread":0.242484274798849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}