{"id":"W2130645032","doi":"10.1074/mcp.m111.016550","title":"An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases","year":2012,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Concordia University; McGill University","funders":"Canadian Institutes of Health Research; University of Saskatchewan; Faculty of Medicine, McGill University; McGill University","keywords":"Foldase; Endoplasmic reticulum; Chaperone (clinical); Cyclophilin; Protein folding; Protein disulfide-isomerase; Isomerase; Cell biology; Cyclophilin A; Chemical chaperone; Co-chaperone; Biology; Unfolded protein response; Chemistry; Biochemistry; Molecular biology; Escherichia coli; Hsp70; Enzyme; Heat shock protein; GroEL","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002382015,0.000187549,0.0002426907,0.00009048329,0.00009581462,0.00001571459,0.0001467839,0.000215509,0.0002131836],"category_scores_gemma":[0.0000241962,0.0001801514,0.00007619965,0.00004820545,0.0001263454,0.0002150726,0.00007985059,0.0002133039,0.00009995791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001724178,"about_ca_system_score_gemma":0.00001717285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004935945,"about_ca_topic_score_gemma":0.000001916734,"domain_scores_codex":[0.9989406,0.000178441,0.0002668892,0.0002259259,0.00003987112,0.0003482858],"domain_scores_gemma":[0.9994045,0.00001829689,0.0001485869,0.000346446,0.00004143213,0.00004074456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006259241,0.0001936421,0.0003780329,0.00003520224,0.00006629691,0.000003333837,0.0004054216,0.000004197445,0.9944068,0.003561825,0.00002521237,0.0008574105],"study_design_scores_gemma":[0.0005578314,0.0003117916,0.000215643,0.0000233081,0.00005189093,0.00005690883,0.0002712974,0.0000329561,0.9932094,0.0001992837,0.004878708,0.0001910105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852535,0.004015406,0.009458348,0.00007040804,0.0006265042,0.0004302135,0.00001532,0.00004175236,0.00008858544],"genre_scores_gemma":[0.9963786,0.0000475678,0.003118361,0.00008172027,0.00002742527,0.0000403553,0.00008314936,0.00003162536,0.0001911933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01112514,"threshold_uncertainty_score":0.7346363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00771278961215385,"score_gpt":0.2211490221397863,"score_spread":0.2134362325276325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}