{"id":"W2130712398","doi":"10.1016/j.ydbio.2011.06.028","title":"Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport","year":2011,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Howard Hughes Medical Institute; Stiftelsen för Strategisk Forskning; Michael Smith Health Research BC; Carl Tryggers Stiftelse för Vetenskaplig Forskning; National Institutes of Health; Vetenskapsrådet; March of Dimes Foundation","keywords":"Biology; Intraflagellar transport; Cilium; Cell biology; Ciliogenesis; Ciliopathy; Profiling (computer programming); Kinase; Genetics; Gene; Flagellum; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309525,0.0002264849,0.0002599287,0.00006694676,0.00008730386,0.000003186192,0.000142336,0.000304793,0.00005039557],"category_scores_gemma":[0.0001102278,0.0002197393,0.0001141115,0.0001036134,0.0002362729,0.000007265362,0.00002996574,0.0000663992,0.00000180695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003023141,"about_ca_system_score_gemma":0.0004326128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004440893,"about_ca_topic_score_gemma":0.00003810663,"domain_scores_codex":[0.9986346,0.00007627838,0.0004216775,0.0004586526,0.00007997859,0.0003288215],"domain_scores_gemma":[0.9994884,0.00001287017,0.0001214526,0.0001202937,0.00008789503,0.0001690897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005754998,0.0001875132,0.02268913,0.00007691282,0.0002249403,0.000005896855,0.0003061487,9.110252e-7,0.9752534,0.0003016643,0.00009044072,0.0002875171],"study_design_scores_gemma":[0.002679697,0.0006892791,0.0177566,0.00004072072,0.00007645082,0.00001798853,0.0004376462,0.00001433206,0.9754178,0.0006985843,0.001800768,0.0003701171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963774,0.0005191907,0.0009245122,0.00005486489,0.00009111713,0.0008322431,0.0006603165,0.00002195947,0.000518373],"genre_scores_gemma":[0.9883319,0.00007346758,0.008483727,0.0001783222,0.00001858539,0.0001502077,0.00256405,0.00002416106,0.0001756049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008045549,"threshold_uncertainty_score":0.8960708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882189864506917,"score_gpt":0.2203920288955769,"score_spread":0.2015701302505078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}