{"id":"W2130712398","doi":"10.1016/j.ydbio.2011.06.028","title":"Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport","year":2011,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Howard Hughes Medical Institute; Stiftelsen för Strategisk Forskning; Michael Smith Health Research BC; Carl Tryggers Stiftelse för Vetenskaplig Forskning; National Institutes of Health; Vetenskapsrådet; March of Dimes Foundation","keywords":"Biology; Intraflagellar transport; Cilium; Cell biology; Ciliogenesis; Ciliopathy; Profiling (computer programming); Kinase; Genetics; Gene; Flagellum; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008986364,0.000427187,0.0002334217,0.0005026468,0.0003437447,0.0003713017,0.0002643991,0.0003395528,0.0013106],"category_scores_gemma":[0.0001264267,0.0002685113,0.0002596385,0.0001549958,0.0003609118,0.0001713884,0.0002550122,0.0005896124,0.00076113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007424177,"about_ca_system_score_gemma":0.0002954792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002340727,"about_ca_topic_score_gemma":0.006237862,"domain_scores_codex":[0.9998763,0.00000420758,0.000006427018,0.00004035724,0.00004269259,0.00003004871],"domain_scores_gemma":[0.9998177,0.00002309552,0.00006228455,0.00001736677,0.00002348805,0.00005606275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009462715,0.00000980489,0.0003900049,0.00001544036,0.000002353075,0.00008867875,0.000008372246,0.00004692118,0.9985856,0.00009180792,0.00005405454,0.0006122894],"study_design_scores_gemma":[0.00002657802,0.00008285248,0.03581465,0.00001848525,0.00002481652,0.0003836343,0.00006899075,0.001964401,0.9580557,0.000121845,0.003422447,0.00001564952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931137,0.0006238093,0.00214127,0.0001287827,0.00004312125,0.00001936366,0.002394146,0.00009406403,0.001441702],"genre_scores_gemma":[0.9883552,0.0004162856,0.002809006,0.0001452141,0.00001095866,0.00002408878,0.003092957,0.0001319363,0.005014296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002340727,"threshold_uncertainty_score":0.005386651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882189864506917,"score_gpt":0.2203920288955769,"score_spread":0.2015701302505078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}