{"id":"W2130746800","doi":"10.1189/jlb.0510249","title":"Robust erythrophagocytosis leads to macrophage apoptosis via a hemin-mediated redox imbalance: role in hemolytic disorders","year":2010,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apoptosis; Phagocytosis; Biology; Hemin; Cell biology; In vitro; Reactive oxygen species; Immunology; Heme; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001671882,0.0002390476,0.000220864,0.000240214,0.000118351,0.000197679,0.0001465421,0.0003353268,0.0004940211],"category_scores_gemma":[0.0001149052,0.00007502001,0.0001606821,0.0001026714,0.0002297721,0.0001486269,0.0002475409,0.0003276905,0.0001225856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001691389,"about_ca_system_score_gemma":0.00006805378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001306574,"about_ca_topic_score_gemma":0.0001121156,"domain_scores_codex":[0.9998971,0.00002563059,0.00001463759,0.00002144136,0.00002134201,0.00001978549],"domain_scores_gemma":[0.9999186,0.000008856829,0.00003379493,0.000006385489,0.00001078769,0.00002142635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003752776,0.00005165156,0.002504142,0.0001393889,0.00001772869,0.001120621,0.00006398452,0.00005246951,0.9925423,0.0002724933,0.00006267237,0.002797184],"study_design_scores_gemma":[0.00005933462,0.001144857,0.1080074,0.0000649734,0.0001264816,0.01133078,0.0003313743,0.001838497,0.8686721,0.0008697973,0.007533008,0.00002155649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900392,0.007150999,0.001809068,0.0001430827,0.00001443318,0.0000208976,0.0001095777,0.0000330529,0.0006797281],"genre_scores_gemma":[0.9964362,0.001928727,0.0007972058,0.00005328916,0.00001510803,0.00001611266,0.00007257977,0.000003203869,0.0006776857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004940211,"threshold_uncertainty_score":0.001652718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01039766164236973,"score_gpt":0.2587412162164043,"score_spread":0.2483435545740346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}