{"id":"W2130748375","doi":"10.1002/etc.5620220324","title":"Hepatic microsomal cytochrome P450 enzyme activity in relation to in vitro metabolism/inhibition of polychlorinated biphenyls and testosterone in Baltic grey seal (<i>Halichoerus grypus</i>)","year":2003,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"","keywords":"Microsome; Metabolism; Cytochrome P450; Chemistry; Biotransformation; Enzyme; Unspecific monooxygenase; Polychlorinated biphenyl; Biochemistry; Stereochemistry; Monooxygenase; Environmental chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222206,0.0002443502,0.0001492973,0.0001720452,0.0001505348,0.0001980008,0.00007989129,0.0001346305,0.0007401631],"category_scores_gemma":[0.000186498,0.0001613294,0.0001764501,0.0001666061,0.0002733722,0.00009489553,0.0001049976,0.0002100685,0.0002323044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002823276,"about_ca_system_score_gemma":0.0001919429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003365997,"about_ca_topic_score_gemma":0.004311348,"domain_scores_codex":[0.9998751,0.00002638738,0.00001046078,0.00003776201,0.00002609213,0.000024161],"domain_scores_gemma":[0.9998441,0.0000206237,0.00004902724,0.00001613495,0.00002979662,0.0000403938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004174272,0.00003048382,0.004689703,0.00003941459,0.00001769001,0.00004913892,0.00007608347,0.00009471693,0.9931971,0.00003188173,0.00002955431,0.00132686],"study_design_scores_gemma":[0.00002955516,0.001730248,0.1090162,0.00000574021,0.0000761884,0.0002364858,0.0001067013,0.000611145,0.887091,0.00004162202,0.001046463,0.000008882416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984679,0.000520742,0.0003886656,0.00002726674,0.000009528758,0.000007917115,0.0001682181,0.00001343751,0.0003963312],"genre_scores_gemma":[0.9959645,0.0005462931,0.0005934871,0.00002513408,0.00001201691,0.00002214376,0.000749727,0.000008092975,0.002078626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003365997,"threshold_uncertainty_score":0.006692827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323671101565885,"score_gpt":0.3070009450125005,"score_spread":0.2837642339968417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}