{"id":"W2130779618","doi":"10.1017/s0031182013002072","title":"Progress and prospects for targeting Hsp90 to treat fungal infections","year":2014,"lang":"en","type":"article","venue":"Parasitology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Hsp90; Drug resistance; Antifungal; Antifungal drug; Pathogen; Drug; Hsp90 inhibitor; Microbiology; Pharmacology; Heat shock protein; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002099345,0.000643028,0.0007332024,0.0008814087,0.0003086051,0.001162187,0.0005775804,0.001343122,0.003393242],"category_scores_gemma":[0.0005845011,0.0001873064,0.0006690698,0.0005448104,0.0007690947,0.002021315,0.0007185569,0.002598756,0.001754022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004618046,"about_ca_system_score_gemma":0.000691704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002216489,"about_ca_topic_score_gemma":0.0005162999,"domain_scores_codex":[0.9997572,0.00006542675,0.00002361945,0.00002893305,0.00006604431,0.00005883078],"domain_scores_gemma":[0.9996666,0.00011465,0.00004918407,0.00001991599,0.00007345941,0.00007620489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001096372,0.001150621,0.001614961,0.004516762,0.0001957936,0.001047407,0.0003070436,0.00169165,0.08819851,0.03120806,0.0571076,0.8118652],"study_design_scores_gemma":[0.0003603803,0.002647347,0.003370906,0.001318566,0.0002664439,0.002048969,0.0002993059,0.001179421,0.02472244,0.02187264,0.9418421,0.00007149804],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008883722,0.9577742,0.005681514,0.01723963,0.00155324,0.0000765475,0.0000772586,0.0001653229,0.008548637],"genre_scores_gemma":[0.02951676,0.9515802,0.00639116,0.00535309,0.002283191,0.0000830024,0.0001971424,0.00003381805,0.004561621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003393242,"threshold_uncertainty_score":0.01135147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123319682865295,"score_gpt":0.3380661630679085,"score_spread":0.3268329662392556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}