{"id":"W2130784601","doi":"10.1136/jcp.56.12.952","title":"Development of immunoglobulin variable heavy chain gene consensus probes with conjugated 3′ minor groove binder groups for monitoring minimal residual disease in childhood acute lymphoblastic leukaemia","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Pathology","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Germline; Minimal residual disease; Immunoglobulin light chain; Minor groove; Antibody; Kappa; Immunoglobulin gene; Immunoglobulin heavy chain; Gene; Consensus sequence; Conjugated system; Molecular biology; Biology; Medicine; Genetics; Immunology; Materials science; DNA; Mathematics; Peptide sequence; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008029966,0.0004010239,0.0003513038,0.0005615879,0.0001615543,0.00029503,0.0005174564,0.0007863723,0.001411651],"category_scores_gemma":[0.001715705,0.0004102812,0.0001830764,0.0002432117,0.0003556825,0.0004824463,0.0003433218,0.0006986331,0.0005203451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004288197,"about_ca_system_score_gemma":0.0003138156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002907391,"about_ca_topic_score_gemma":0.0006552769,"domain_scores_codex":[0.9994029,0.0001458601,0.00003813079,0.0001700234,0.0001723514,0.00007073423],"domain_scores_gemma":[0.9991842,0.0002999375,0.0002038926,0.00007855957,0.0001454405,0.00008794035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002257134,0.00003765827,0.001747597,0.0001054675,0.000008021733,0.00006449466,0.00004250042,0.0003646015,0.9752271,0.000171862,0.000106858,0.02189811],"study_design_scores_gemma":[0.0001178101,0.001194377,0.008468544,0.00003445514,0.00004233043,0.001368842,0.00005462355,0.004036842,0.9788083,0.0002473931,0.005606656,0.00001973617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9155841,0.002683424,0.0781117,0.0003902961,0.00004832902,0.0002211431,0.0003569239,0.0004632515,0.002140766],"genre_scores_gemma":[0.8324478,0.001195484,0.1626489,0.0003258011,0.00002220776,0.0003433455,0.001136817,0.00008304415,0.001796558],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001411651,"threshold_uncertainty_score":0.004722416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03681162341938454,"score_gpt":0.3424882785294667,"score_spread":0.3056766551100822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}