{"id":"W2130881567","doi":"10.1042/bj20101286","title":"The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity","year":2010,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Metal-Catalyzed Oxygenation Mechanisms","field":"Chemistry","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Cancerfonden; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; National Institute for Health and Care Research; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"Glutaredoxin; Oxidoreductase; Chemistry; Cysteine; Glutathione; Biochemistry; Iron–sulfur cluster; Dithiol; Protein structure; Stereochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003185339,0.0004854748,0.0004548432,0.0001651741,0.0004272289,0.0006403902,0.0008009345,0.0006761756,0.003356438],"category_scores_gemma":[0.0003482746,0.000271731,0.0002787364,0.0004486968,0.0001970161,0.0003973019,0.0002996626,0.0008479212,0.0008795425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001301427,"about_ca_system_score_gemma":0.000646373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007263967,"about_ca_topic_score_gemma":0.004861649,"domain_scores_codex":[0.999797,0.00002180243,0.0000154729,0.00005683885,0.0000799524,0.00002881211],"domain_scores_gemma":[0.9998695,0.00001320717,0.0000226642,0.000009308485,0.00004098754,0.00004432947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002754878,0.0006629623,0.008065508,0.00116273,0.0002456607,0.0009361146,0.001206622,0.005672061,0.9005976,0.00273975,0.0224881,0.05346812],"study_design_scores_gemma":[0.001657656,0.001843661,0.1368723,0.0004595273,0.000761538,0.004061677,0.001582178,0.1180906,0.5509939,0.001767803,0.1816038,0.0003054126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708135,0.01034832,0.005269197,0.001085246,0.0001939386,0.0001331673,0.003908318,0.0006799513,0.00756841],"genre_scores_gemma":[0.954441,0.003264271,0.01285828,0.0005558887,0.00005435481,0.00007997865,0.01999019,0.0001207592,0.008635283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007263967,"threshold_uncertainty_score":0.01444334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008621941812411386,"score_gpt":0.2617431034726313,"score_spread":0.2531211616602199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}