{"id":"W2130881567","doi":"10.1042/bj20101286","title":"The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity","year":2010,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Metal-Catalyzed Oxygenation Mechanisms","field":"Chemistry","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Cancerfonden; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; National Institute for Health and Care Research; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust","keywords":"Glutaredoxin; Oxidoreductase; Chemistry; Cysteine; Glutathione; Biochemistry; Iron–sulfur cluster; Dithiol; Protein structure; Stereochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027975,0.0001912002,0.0002121777,0.0000576421,0.0003146427,0.00013752,0.0003488447,0.0002568101,0.0006354534],"category_scores_gemma":[0.0002562143,0.0001374659,0.0001063107,0.00009626587,0.0002096397,0.0001497547,0.00008702891,0.0009820227,0.000003290704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004242981,"about_ca_system_score_gemma":0.00006222857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005799591,"about_ca_topic_score_gemma":0.000004347919,"domain_scores_codex":[0.9986401,0.00003637988,0.0003700747,0.000229257,0.0004634328,0.0002607702],"domain_scores_gemma":[0.9987882,0.0001301803,0.0003960759,0.0003016198,0.0001808056,0.0002031469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003115199,0.00004233749,0.0002899707,0.00002715415,0.00003868429,0.000001539533,0.00005272152,5.635836e-7,0.9964999,0.0002014874,0.001079814,0.001734705],"study_design_scores_gemma":[0.0006002336,0.00001904501,0.0009197912,0.00001072203,0.00003149669,0.0002131867,0.0000856449,0.00007858156,0.9955386,0.001067549,0.00127236,0.00016279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981425,0.00007881975,0.0004624143,0.0002948455,0.0001695745,0.00005671379,0.00004654458,0.00001899644,0.0007296316],"genre_scores_gemma":[0.9980814,0.00001607872,0.001182261,0.00003398562,0.0003934142,0.000002364316,0.00002110678,0.00002448207,0.0002448507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001571915,"threshold_uncertainty_score":0.6957769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008621941812411386,"score_gpt":0.2617431034726313,"score_spread":0.2531211616602199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}