{"id":"W2130891215","doi":"10.1093/hmg/ddl002","title":"A role for Brca1 in chromosome end maintenance","year":2006,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Telomere; Biology; Chromosomal translocation; Carcinogenesis; Phenotype; Genetics; Cancer research; DNA damage; DNA repair; Genome instability; Chromosome; Cell biology; DNA; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002049528,0.0002135637,0.0001923261,0.0003018613,0.0003304859,0.0006007061,0.0002603869,0.0004006695,0.001672175],"category_scores_gemma":[0.0003121021,0.00009819467,0.0001338987,0.0001158398,0.000273907,0.000384063,0.0002897498,0.0003795128,0.0007067473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003754662,"about_ca_system_score_gemma":0.0002692034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004553965,"about_ca_topic_score_gemma":0.0003361374,"domain_scores_codex":[0.9999422,0.00001028531,0.00000315718,0.00001737738,0.00001359303,0.00001344974],"domain_scores_gemma":[0.9998148,0.00003591087,0.00005343172,0.00001866314,0.00002585761,0.00005142395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000372614,0.00006149612,0.005807108,0.0003093893,0.00002556362,0.001164759,0.00009736582,0.0007316835,0.9465829,0.006690975,0.001022703,0.03713335],"study_design_scores_gemma":[0.00004776664,0.0007280289,0.03913261,0.0001111197,0.00004999455,0.01004069,0.0001153698,0.003561398,0.8889101,0.006056124,0.05121326,0.00003349764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8862138,0.08338497,0.01440672,0.002373293,0.000206739,0.00003984259,0.0008947497,0.0003885601,0.01209129],"genre_scores_gemma":[0.9825247,0.008671783,0.003250337,0.0001629212,0.00004666219,0.000008961472,0.0003344102,0.000008600921,0.004991656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001672175,"threshold_uncertainty_score":0.005594015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128635892151681,"score_gpt":0.2589081065824927,"score_spread":0.2476217476609759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}