{"id":"W2130926483","doi":"10.1105/tpc.104.026039","title":"Novel Targeting Signals Mediate the Sorting of Different Isoforms of the Tail-Anchored Membrane Protein Cytochrome <i>b</i><sub><i>5</i></sub> to Either Endoplasmic Reticulum or Mitochondria","year":2004,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Guelph","funders":"","keywords":"Endoplasmic reticulum; Protein targeting; Biology; Biochemistry; Protein Sorting Signals; Cell biology; Mitochondrion; Organelle; Membrane protein; Gene isoform; Transmembrane protein; Peptide sequence; Signal peptide; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004140058,0.0002738827,0.0003099458,0.00002854205,0.0001705325,0.00001918561,0.0007785009,0.0001235942,0.00001547521],"category_scores_gemma":[0.0001883223,0.0001183925,0.0002043776,0.0001709319,0.0001331159,0.000005057246,0.0003115966,0.000187964,0.000005207501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000142169,"about_ca_system_score_gemma":0.0001410861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004366575,"about_ca_topic_score_gemma":0.000108864,"domain_scores_codex":[0.9983201,0.00006045413,0.000509224,0.0003296845,0.0003472651,0.0004332596],"domain_scores_gemma":[0.9987305,0.00006434073,0.0004615229,0.0005762056,0.00008597338,0.00008145181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002541188,0.0001337477,0.000003595767,0.0001123799,0.00005869796,0.000001404469,0.0004891503,0.0005049311,0.9982767,0.00006885098,0.00003282474,0.00006362431],"study_design_scores_gemma":[0.0007607227,0.0002833416,0.0000177709,0.0001753543,0.00007212645,0.00002997365,0.0003459012,0.00006069005,0.9974824,0.000355659,0.0002274736,0.0001885659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955302,0.0001332771,0.002142916,0.000449096,0.0001591315,0.001194419,0.0001777845,0.000011417,0.000201772],"genre_scores_gemma":[0.9989209,0.00009902661,0.0002496787,0.0002936767,0.0001219447,0.0001313385,0.00002829697,0.00003860073,0.0001165802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00339067,"threshold_uncertainty_score":0.4827905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007799034334270067,"score_gpt":0.1922788595842676,"score_spread":0.1844798252499976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}