{"id":"W2130926483","doi":"10.1105/tpc.104.026039","title":"Novel Targeting Signals Mediate the Sorting of Different Isoforms of the Tail-Anchored Membrane Protein Cytochrome <i>b</i><sub><i>5</i></sub> to Either Endoplasmic Reticulum or Mitochondria","year":2004,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Guelph","funders":"","keywords":"Endoplasmic reticulum; Protein targeting; Biology; Biochemistry; Protein Sorting Signals; Cell biology; Mitochondrion; Organelle; Membrane protein; Gene isoform; Transmembrane protein; Peptide sequence; Signal peptide; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831641,0.0003611334,0.0001669432,0.0001297237,0.0001671163,0.0003588926,0.0002231879,0.0002486911,0.0003656252],"category_scores_gemma":[0.0001506771,0.0001817037,0.0003060414,0.0001288369,0.0002828424,0.0003135094,0.000357832,0.000397301,0.0002700481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005288586,"about_ca_system_score_gemma":0.0001761224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009358823,"about_ca_topic_score_gemma":0.0009556718,"domain_scores_codex":[0.9998598,0.00001900568,0.0000160244,0.00004361586,0.0000283172,0.00003316095],"domain_scores_gemma":[0.9998317,0.00002380654,0.00006647964,0.00001864668,0.00001910047,0.00004030806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005613587,0.000005677692,0.000305804,0.00001682782,0.000002418216,0.00003615497,0.00001243469,0.0000156087,0.9988148,0.000119383,0.00001099751,0.0006038333],"study_design_scores_gemma":[0.00001533233,0.0001223337,0.009116589,0.00000518068,0.00002069752,0.0004117239,0.00004595069,0.0009440584,0.9875488,0.00004316865,0.001720945,0.000005211517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954497,0.0007621004,0.003028546,0.00003191607,0.000009923665,0.00001875195,0.0000899396,0.00003749691,0.0005716737],"genre_scores_gemma":[0.9949027,0.0003520642,0.003136746,0.00004121159,0.000005704987,0.0000108197,0.0003850819,0.00001400238,0.001151597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009358823,"threshold_uncertainty_score":0.003837168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007799034334270067,"score_gpt":0.1922788595842676,"score_spread":0.1844798252499976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}