{"id":"W2131086685","doi":"10.1210/en.2007-0361","title":"Synergistic Effects of Epidermal Growth Factor and Hepatocyte Growth Factor on Human Ovarian Cancer Cell Invasion and Migration: Role of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of British Columbia","keywords":"Hepatocyte growth factor; Epidermal growth factor; MAPK/ERK pathway; Cancer research; Protein kinase B; Ovarian cancer; Biology; Growth factor; Autocrine signalling; Kinase; Protein kinase A; Signal transduction; Cell biology; Endocrinology; Internal medicine; Cancer; Medicine; Cell culture; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001546452,0.0003376707,0.0001759682,0.0001775319,0.00008740393,0.0001479131,0.00008311465,0.0001501483,0.0009069709],"category_scores_gemma":[0.000130475,0.0001075702,0.0002419738,0.000103412,0.0001155869,0.0001477724,0.0002511782,0.0002496016,0.0001606843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000129083,"about_ca_system_score_gemma":0.0002409273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002542919,"about_ca_topic_score_gemma":0.0007864487,"domain_scores_codex":[0.9998354,0.00004945382,0.00001049862,0.00001453475,0.00004128767,0.0000488374],"domain_scores_gemma":[0.9999199,0.00001972714,0.00001378634,0.000007795031,0.000008676279,0.00003005088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001012102,0.0001501165,0.001072097,0.0001794334,0.00002472481,0.0002195003,0.0000255869,0.0001423045,0.9900393,0.00008931234,0.0001129642,0.00693255],"study_design_scores_gemma":[0.0001225577,0.003072883,0.0260351,0.00002423203,0.0001119357,0.001109385,0.000102375,0.001842221,0.9632097,0.0001022249,0.004255008,0.00001233418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911993,0.00598288,0.0007542173,0.0001083437,0.00004404388,0.00002689295,0.00007797957,0.00002916781,0.001777165],"genre_scores_gemma":[0.996696,0.001267474,0.0009860465,0.00004427905,0.00001727837,0.00002703551,0.0000951756,0.000002659973,0.0008641855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009069709,"threshold_uncertainty_score":0.003034115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01289217148316396,"score_gpt":0.2511293095207689,"score_spread":0.2382371380376049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}