{"id":"W2131112498","doi":"10.4049/jimmunol.167.8.4686","title":"AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-γ Receptor-Deficient Mice","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":253,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity Western University","funders":"","keywords":"C-C chemokine receptor type 6; Chemokine receptor; Stromal cell-derived factor 1; Inflammation; Stromal cell; Immunology; Cancer research; CC chemokine receptors; Receptor; CXCR4; CCR1; CCL21; Chemokine; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472435,0.000462812,0.0004971523,0.0003050539,0.000126523,0.0002075294,0.0002719152,0.0003447299,0.0006516299],"category_scores_gemma":[0.0001879153,0.0001671517,0.0002036684,0.0001129976,0.0002302467,0.0001432614,0.0001075828,0.0005946187,0.0002689158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796756,"about_ca_system_score_gemma":0.0002686506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004622448,"about_ca_topic_score_gemma":0.000728906,"domain_scores_codex":[0.9998487,0.00003215463,0.0000139604,0.00001631753,0.00002943985,0.00005942018],"domain_scores_gemma":[0.9998825,0.00001873316,0.00003717524,0.00001249515,0.000009365176,0.00003968679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006513285,0.0002695599,0.0002988873,0.00005204385,0.000007982682,0.00005561733,0.00001334457,0.0002037578,0.9934313,0.0000829333,0.0001233685,0.004809938],"study_design_scores_gemma":[0.0006511048,0.009579791,0.008192474,0.00001509547,0.00004918142,0.0007346144,0.00001976981,0.003068649,0.9744595,0.0001277727,0.003087936,0.00001419358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954969,0.001720149,0.001232486,0.000112199,0.00003534986,0.00006009763,0.0002257431,0.0001622603,0.0009547995],"genre_scores_gemma":[0.994938,0.0008896156,0.001809098,0.00006328867,0.00002715752,0.0001049727,0.0004779775,0.00001372253,0.001676149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006516299,"threshold_uncertainty_score":0.002179921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01640010312837318,"score_gpt":0.2245822514443541,"score_spread":0.2081821483159809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}