{"id":"W2131163278","doi":"10.1038/labinvest.3700335","title":"An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line","year":2005,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; St. Joseph’s Healthcare Hamilton; Hamilton Health Sciences; Hamilton General Hospital; Ontario Institute for Cancer Research; BC Cancer Agency","funders":"Medical Research and Materiel Command; Canadian Institutes of Health Research; National Cancer Institute; Prostate Cancer Foundation; U.S. Department of Defense","keywords":"Prostate cancer; Pathology; Metastasis; Prostate; Medicine; Cancer; PCA3; Lymph; Renal capsule; Immunohistochemistry; Cancer research; Transplantation; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001782597,0.0001197646,0.0001316269,0.00007013038,0.00005887127,0.00001667256,0.00008549874,0.00003343305,0.000008444692],"category_scores_gemma":[0.00001117928,0.0001167596,0.00002111693,0.0002182597,0.00008443464,0.00003032771,0.00001218227,0.00007775849,0.000001898156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004516853,"about_ca_system_score_gemma":0.000316462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006291175,"about_ca_topic_score_gemma":0.007206751,"domain_scores_codex":[0.9990528,0.00007758546,0.0002484342,0.0002603895,0.000141588,0.0002192602],"domain_scores_gemma":[0.9994925,0.000003100385,0.0001030071,0.0001676741,0.0001276934,0.0001059842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007910026,0.00008016908,0.03642251,0.00008912093,0.00002568283,0.000004307151,0.0004668939,0.007945634,0.9545098,0.00002277734,0.00001479617,0.0003392322],"study_design_scores_gemma":[0.00130993,0.0002494547,0.002530973,0.00006368256,0.00002391486,0.000001543604,0.00003535302,0.01136468,0.9838688,0.0002485125,0.0001642504,0.0001389276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985718,0.0005210156,0.000109564,0.00008448192,0.00001171721,0.0004031932,0.0002708911,0.00001020036,0.00001718974],"genre_scores_gemma":[0.997044,0.00008673369,0.001889019,0.0001931197,0.00004208076,0.0001832538,0.0004859098,0.00001865409,0.0000571916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03389153,"threshold_uncertainty_score":0.4761317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01665671124480727,"score_gpt":0.307235381344279,"score_spread":0.2905786700994717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}