{"id":"W2131170758","doi":"10.1074/jbc.m701454200","title":"Secondary Acylation of Klebsiella pneumoniae Lipopolysaccharide Contributes to Sensitivity to Antibacterial Peptides","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Klebsiella pneumoniae; Acylation; Microbiology; Lipopolysaccharide; Antibacterial activity; Chemistry; Klebsiella; Escherichia coli; Medicine; Bacteria; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001459722,0.0003472558,0.0002349041,0.0001488467,0.00009588739,0.0003681258,0.0001422504,0.0003398415,0.001072829],"category_scores_gemma":[0.0002730377,0.000151887,0.00021102,0.00009513037,0.0001773669,0.0001443141,0.0003155401,0.0003811287,0.0004711077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002055428,"about_ca_system_score_gemma":0.000129872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005139394,"about_ca_topic_score_gemma":0.0003441499,"domain_scores_codex":[0.9997985,0.00003838887,0.00002670728,0.00002779885,0.00004586298,0.00006271357],"domain_scores_gemma":[0.9996152,0.00005495333,0.000116914,0.00003929656,0.00004777853,0.000125866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102111,0.00001086029,0.0005893555,0.00001427395,0.00000219094,0.00005123928,0.000006871653,0.00001814562,0.9988139,0.00001258387,0.000009767836,0.0003687871],"study_design_scores_gemma":[0.0000186894,0.0006579731,0.06207145,0.0000117735,0.00002809837,0.001611413,0.00006617747,0.0006586571,0.9336812,0.00007191249,0.001111214,0.00001151243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989185,0.0003492301,0.0002984749,0.0000244788,0.000004559356,0.000004585249,0.00007304313,0.00001048569,0.0003165912],"genre_scores_gemma":[0.9990019,0.0001310818,0.0002661897,0.00002220775,0.000002511694,0.000004360361,0.0001762476,0.000005520251,0.000390042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072829,"threshold_uncertainty_score":0.003588974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127612882070223,"score_gpt":0.2429877080943709,"score_spread":0.2302264198873486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}