{"id":"W2131170758","doi":"10.1074/jbc.m701454200","title":"Secondary Acylation of Klebsiella pneumoniae Lipopolysaccharide Contributes to Sensitivity to Antibacterial Peptides","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Klebsiella pneumoniae; Acylation; Microbiology; Lipopolysaccharide; Antibacterial activity; Chemistry; Klebsiella; Escherichia coli; Medicine; Bacteria; Biology; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008776726,0.0001724823,0.0005309017,0.00007262627,0.00007655468,0.00001669787,0.0001643503,0.0003235514,0.0002301281],"category_scores_gemma":[0.0004763972,0.0001290411,0.0001972292,0.0001026405,0.000175728,0.00007429971,0.0001158747,0.0003604219,0.00002469225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000484995,"about_ca_system_score_gemma":0.00006209948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002188287,"about_ca_topic_score_gemma":0.000005370731,"domain_scores_codex":[0.9987648,0.00006391521,0.000631611,0.0001770528,0.0000433306,0.000319308],"domain_scores_gemma":[0.9988005,0.0003760454,0.0003968162,0.0001234574,0.0002345631,0.00006860875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000878669,0.0001103614,0.004498378,0.00002179557,0.0001027703,0.00002533533,0.00006982542,0.000008910945,0.9893487,0.00002588505,0.001210451,0.003698936],"study_design_scores_gemma":[0.00049197,0.0002771846,0.02273121,0.00008707804,0.0000225655,0.0002305271,0.0002816691,1.990368e-7,0.971688,0.00006392565,0.003985293,0.0001404185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967415,0.0001529194,0.001639366,0.0004594014,0.0004147179,0.00008995846,0.0000685107,0.000014669,0.0004189296],"genre_scores_gemma":[0.9988248,0.00003004195,0.0003523775,0.0002990752,0.0002234984,4.254418e-7,0.00001672928,0.000007473352,0.000245581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01823284,"threshold_uncertainty_score":0.5262144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127612882070223,"score_gpt":0.2429877080943709,"score_spread":0.2302264198873486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}