{"id":"W2131178461","doi":"10.1634/theoncologist.2010-0137","title":"Treatment Beyond Progression: Is It Moving from Belief to Evidence?","year":2010,"lang":"en","type":"letter","venue":"The Oncologist","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Trastuzumab; Metastatic breast cancer; Breast cancer; Oncology; MEDLINE; Internal medicine; Family medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.000620178,0.0005099917,0.000896127,0.0001442987,0.0002924904,0.0001347947,0.0009638463,0.001764994,0.006573674],"category_scores_gemma":[0.00072297,0.0002796036,0.0002680203,0.000288596,0.0005526681,0.00005155307,0.0004449556,0.004836522,0.002616575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001883369,"about_ca_system_score_gemma":0.001587401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00351004,"about_ca_topic_score_gemma":0.0005733221,"domain_scores_codex":[0.996123,0.0002860932,0.0004889391,0.0008984025,0.001344881,0.0008587433],"domain_scores_gemma":[0.995799,0.001497507,0.0002131481,0.002002309,0.0002151642,0.0002728397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001928228,0.0001065005,0.0006398753,0.00009342603,0.0001495493,0.002094521,0.001047804,2.967721e-7,0.0007517574,0.000001697158,0.9223214,0.07260029],"study_design_scores_gemma":[0.0006327607,0.002744675,0.0005022687,0.001124419,0.0002944967,0.00008465634,0.0001034121,0.00001215312,0.001802578,0.0001267034,0.9922872,0.0002846578],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.004025612,0.002216559,0.000009061978,0.9682551,0.001222006,0.002618904,0.0001714337,0.0001098632,0.02137143],"genre_scores_gemma":[0.002609836,0.0009955929,0.002568707,0.8958049,0.01852275,0.001489912,0.00019518,0.0001312524,0.07768183],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07245019,"threshold_uncertainty_score":0.9999656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1771967083120371,"score_gpt":0.4723174421791335,"score_spread":0.2951207338670965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}