{"id":"W2131236523","doi":"10.1017/s1461145708009012","title":"Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder","year":2008,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Center for Research Resources; National Institutes of Health; National Institute of Mental Health; Eli Lilly and Company","keywords":"Prefrontal cortex; Major depressive disorder; 5-HT1A receptor; Internal medicine; Endocrinology; Psychology; Receptor; Dorsolateral prefrontal cortex; Neuroscience; Biology; 5-HT receptor; Medicine; Serotonin; Amygdala; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002406926,0.000107333,0.0001384442,0.00008895283,0.00003872012,0.00001022807,0.0004665641,0.00004777486,0.00009033162],"category_scores_gemma":[0.00003662836,0.00006234183,0.00004979026,0.0000740011,0.0001274911,0.00001074132,0.00005227225,0.0002293973,7.420448e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001271629,"about_ca_system_score_gemma":0.0000909747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002135446,"about_ca_topic_score_gemma":0.0000325758,"domain_scores_codex":[0.998952,0.0002142427,0.0003175202,0.0001483241,0.0002424297,0.0001254651],"domain_scores_gemma":[0.9993914,0.0000579556,0.0002704482,0.00009611547,0.0001402084,0.0000438494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002409844,0.0002167607,0.007157524,0.000002927276,0.00008364423,0.0001766071,0.0005096447,0.0001574114,0.9882622,0.00004670094,0.00034093,0.0006358175],"study_design_scores_gemma":[0.02252881,0.003888526,0.5106113,0.0001144255,0.00009828755,0.007920443,0.001367832,0.000240663,0.4390601,0.0006328632,0.01301453,0.0005222042],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974877,0.001049534,0.0002947682,0.0004882758,0.0003245118,0.0002243161,0.000006839939,0.000001031718,0.000123069],"genre_scores_gemma":[0.9975447,0.001441723,0.0002447712,0.0005090686,0.0002065855,0.00001419855,0.000004009893,0.00001239847,0.00002251663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5492021,"threshold_uncertainty_score":0.2542226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015482597069599,"score_gpt":0.266424199696392,"score_spread":0.250941602626793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}