{"id":"W2131239755","doi":"10.1089/107999000312540","title":"Transforming Growth Factor- <i>beta</i> mRNA and Protein in Hypertrophic Scar Tissues and Fibroblasts: Antagonism by IFN- <i>alpha</i> and IFN- <i>gamma</i> <i>In Vitro</i> and <i>In Vivo</i>","year":2000,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Wound healing; Fibroblast; Cytokine; Transforming growth factor; Molecular biology; In vitro; In vivo; Hypertrophic scar; Transforming growth factor beta; Chemistry; Fibrosis; Hydroxyproline; Growth factor; Immunology; Biology; Pathology; Endocrinology; Medicine; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001318342,0.0003924605,0.0009987558,0.000767639,0.0001286012,0.000141271,0.0001422178,0.0002317138,0.00004269812],"category_scores_gemma":[0.00005212412,0.0003155838,0.00006962904,0.0004257625,0.0003707129,0.0004865587,0.00007393997,0.001521904,0.000002247505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003280262,"about_ca_system_score_gemma":0.000198426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003092331,"about_ca_topic_score_gemma":0.001719267,"domain_scores_codex":[0.9965899,0.0003087342,0.0009999981,0.0005390987,0.0007356794,0.0008265943],"domain_scores_gemma":[0.9987785,0.0002631403,0.0001287012,0.0001936439,0.0001566023,0.0004794702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01035412,0.0007360976,0.03951487,0.0006602389,0.0001056347,0.001403943,0.002539798,0.000001903957,0.9223475,0.00001035867,0.0004984183,0.02182709],"study_design_scores_gemma":[0.03208004,0.01065789,0.01456055,0.007260749,0.0001132781,0.005180047,0.001158782,0.0001894387,0.9115038,0.0004876102,0.01598165,0.0008261681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863732,0.008955475,0.000003644446,0.003047456,0.00003191212,0.0007943476,0.0000509018,0.00001209732,0.0007309652],"genre_scores_gemma":[0.9895732,0.008965384,0.0002598912,0.0001635311,0.0001109556,0.00002726956,0.000005833162,0.00005423766,0.0008396403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02495432,"threshold_uncertainty_score":0.9999296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02450213876451365,"score_gpt":0.3143159733457041,"score_spread":0.2898138345811905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}