{"id":"W2131254236","doi":"10.1093/toxsci/kfs098","title":"Effects of Chronic Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants on the Reproductive and Thyroid System in Adult Male Rats","year":2012,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Congener; Polybrominated diphenyl ethers; Thyroid; Brominated flame retardant; Hexabromocyclododecane; Endocrinology; Internal medicine; Toxicity; Thyroid function; Diphenyl ether; Physiology; Hormone; Testosterone (patch); Chemistry; Sperm; Reproductive toxicity; Biology; Fire retardant; Medicine; Andrology; Environmental chemistry; Pollutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001637244,0.0005974572,0.0003947984,0.0005614509,0.0002531844,0.0002577136,0.000251268,0.0004039087,0.001268066],"category_scores_gemma":[0.000113389,0.0003559975,0.0004981549,0.0002034716,0.0004641358,0.0002458667,0.0002661752,0.0007572604,0.0002520764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003846388,"about_ca_system_score_gemma":0.0004482842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003404746,"about_ca_topic_score_gemma":0.005973466,"domain_scores_codex":[0.999719,0.00003070505,0.00001876799,0.00008904454,0.00006293085,0.00007959576],"domain_scores_gemma":[0.9997415,0.00001760819,0.00007430198,0.00002702527,0.00004235869,0.0000972954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00243747,0.0005893472,0.003126771,0.00004782591,0.0000430679,0.0001478053,0.00009475774,0.0001321797,0.9901911,0.00005195698,0.0001028075,0.003034824],"study_design_scores_gemma":[0.0001312193,0.01931387,0.05180282,0.00001772859,0.0002181959,0.000493995,0.0003801059,0.0007829788,0.924426,0.0001207159,0.002265179,0.00004719137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997932,0.0005914453,0.0005948598,0.00005903417,0.00003610845,0.00002591159,0.0003091008,0.00003950638,0.0004120131],"genre_scores_gemma":[0.9918291,0.001093056,0.001326453,0.0001219999,0.00002224286,0.00008665996,0.0005933731,0.00001851644,0.004908699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003404746,"threshold_uncertainty_score":0.006769836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009760709141561224,"score_gpt":0.227729872014563,"score_spread":0.2179691628730018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}