{"id":"W2131352716","doi":"10.1200/jco.2004.08.174","title":"Response to Paclitaxel, Topotecan, and Topotecan-Cyclophosphamide in Children With Untreated Disseminated Neuroblastoma Treated in an Upfront Phase II Investigational Window: A Pediatric Oncology Group Study","year":2004,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Topotecan; Medicine; Cyclophosphamide; Internal medicine; Chemotherapy; Neuroblastoma; Transplantation; Paclitaxel; Surgery; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006918092,0.0004463451,0.000788837,0.0002775077,0.0003278552,0.000446356,0.0003772498,0.0005639999,0.0005003292],"category_scores_gemma":[0.001213075,0.0002118171,0.0004796601,0.0005014527,0.000464006,0.0002686664,0.0001787465,0.0008024693,0.0001047761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001052894,"about_ca_system_score_gemma":0.000886504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002050993,"about_ca_topic_score_gemma":0.002753962,"domain_scores_codex":[0.9994859,0.0002204799,0.00003811287,0.00009631486,0.00008200637,0.00007725209],"domain_scores_gemma":[0.9989645,0.0002738824,0.0003474397,0.00005512897,0.00006578967,0.0002931995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01587381,0.003505654,0.9462524,0.0001307687,0.0004994887,0.001892394,0.000467003,0.0007292596,0.008926593,0.00007183263,0.0007890329,0.02086168],"study_design_scores_gemma":[0.005120681,0.04186255,0.938431,0.00004378102,0.0004829124,0.006370354,0.0003106943,0.000857233,0.004129779,0.00004606965,0.002323415,0.0000216199],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99926,0.0003991202,0.00003194524,0.00003556486,0.000003326012,0.00002892531,0.0001133582,0.000002806631,0.0001249251],"genre_scores_gemma":[0.9982856,0.0004253658,0.0002419486,0.0001263162,0.00002449882,0.00007539572,0.0007021066,0.00000405539,0.0001147311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002050993,"threshold_uncertainty_score":0.007639349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04608675601567265,"score_gpt":0.4334858786762363,"score_spread":0.3873991226605637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}