{"id":"W2131416851","doi":"10.4049/jimmunol.1303083","title":"Intestinal Expression of Fas and Fas Ligand Is Upregulated by Bacterial Signaling through TLR4 and TLR5, with Activation of Fas Modulating Intestinal TLR-Mediated Inflammation","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Fas ligand; TLR5; TLR4; Intestinal epithelium; TLR2; Biology; Cell biology; Apoptosis; Toll-like receptor; Inflammation; Signal transduction; Receptor; Fas receptor; Immunology; Epithelium; Immune system; Innate immune system; Programmed cell death; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002400173,0.0003725197,0.000269197,0.0005450672,0.0001520562,0.0004396109,0.0001372608,0.0003581191,0.002778293],"category_scores_gemma":[0.0002286102,0.0001797013,0.0004200055,0.0002407519,0.0002208343,0.0003657912,0.0003739036,0.0004680318,0.0005384678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003242411,"about_ca_system_score_gemma":0.0001791812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002597797,"about_ca_topic_score_gemma":0.00026616,"domain_scores_codex":[0.9996029,0.00007836026,0.00005811534,0.00005321725,0.0001213927,0.00008598701],"domain_scores_gemma":[0.9997594,0.00001586841,0.0001188052,0.00001650976,0.00004535447,0.00004405701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003484041,0.0000233361,0.002678435,0.0001994092,0.00002458558,0.0002031259,0.00003951211,0.00006691331,0.9893167,0.0001622689,0.00005623049,0.006881198],"study_design_scores_gemma":[0.00008531121,0.001679881,0.05744149,0.00008945792,0.0001537618,0.002714887,0.0003564016,0.001435122,0.922086,0.0005036475,0.01342563,0.00002842269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790277,0.0117372,0.005845862,0.0002104144,0.00006728591,0.00004187914,0.0002781568,0.0001018066,0.002689637],"genre_scores_gemma":[0.9898224,0.003278246,0.003189305,0.00009352217,0.00002442637,0.00003235944,0.0003449364,0.00000829595,0.003206503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002778293,"threshold_uncertainty_score":0.009294331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007537679788040544,"score_gpt":0.2090576748535213,"score_spread":0.2015199950654808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}