{"id":"W2131466702","doi":"10.1186/1532-429x-15-38","title":"Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone","year":2013,"lang":"en","type":"article","venue":"Journal of Cardiovascular Magnetic Resonance","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health; New England Research Institutes; American University of Beirut; Harvard Catalyst; Bunning Food Allergy Institute, Ann and Robert H. Lurie Children's Hospital of Chicago; Children's Hospital of Philadelphia","keywords":"Medicine; Deferiprone; Ejection fraction; Deferoxamine; Internal medicine; Heart failure; Thalassemia; Clinical endpoint; Chelation therapy; Placebo; Combination therapy; Prospective cohort study; Cardiology; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004485402,0.0002740289,0.001368069,0.0003439984,0.00002069378,0.0000142912,0.0001033277,0.0001316827,0.00004839609],"category_scores_gemma":[0.0001637933,0.0001475589,0.0003426877,0.0006636688,0.0000855519,0.000111902,0.00001547346,0.0002238892,0.000006283483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002027533,"about_ca_system_score_gemma":0.0002944195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002376801,"about_ca_topic_score_gemma":0.00007426182,"domain_scores_codex":[0.9975778,0.0002802883,0.0007232817,0.000268302,0.0008055597,0.0003448112],"domain_scores_gemma":[0.9986539,0.00009020336,0.000165984,0.0004651362,0.0004046042,0.0002201842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3886169,0.001496951,0.5192687,0.0002683453,0.0007570001,0.0007921316,0.002226282,0.0009730349,0.0003395076,7.544571e-7,0.0003576014,0.08490283],"study_design_scores_gemma":[0.1507388,0.02498449,0.7963635,0.00216932,0.0003901889,0.0005465823,0.0006671842,0.00006429765,0.0003895729,0.000001410766,0.02347123,0.0002134812],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715973,0.02563373,0.00003007221,0.0005711295,0.00003033462,0.002046945,0.000002426374,0.000005875394,0.0000821675],"genre_scores_gemma":[0.992776,0.001854351,0.004977036,0.00006107169,0.00002731073,0.00008988116,0.000001676875,0.00003844903,0.0001742626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2770948,"threshold_uncertainty_score":0.6017279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004014198088807259,"score_gpt":0.2003149007033205,"score_spread":0.1963007026145132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}