{"id":"W2131476982","doi":"10.1016/j.pep.2010.01.008","title":"Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin","year":2010,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Michigan","keywords":"Transferrin; Chemistry; Cleavage (geology); Protease; Biochemistry; Lobe; Chromatography; Biology; Enzyme; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002640423,0.00009070549,0.0002203067,0.00004706761,0.0000646202,0.000005326322,0.00007742336,0.00008892279,0.0000364068],"category_scores_gemma":[0.0000773198,0.00005660806,0.00004398846,0.00009305975,0.000210055,0.0000640588,0.00001422044,0.0001196785,7.049532e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002381566,"about_ca_system_score_gemma":0.0000191093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001133871,"about_ca_topic_score_gemma":0.000005234908,"domain_scores_codex":[0.9991214,0.00007476769,0.0003483054,0.00017181,0.0001999167,0.00008381285],"domain_scores_gemma":[0.9993427,0.000009104456,0.0001785139,0.0003294345,0.0001011628,0.00003902089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001954067,0.0001489057,0.002436183,0.0004435333,0.000006664821,4.247236e-8,0.001741797,3.55763e-7,0.9857922,0.000114439,0.000294521,0.008825959],"study_design_scores_gemma":[0.0006095715,0.0001462365,0.007701981,0.00008525873,0.00005721757,0.000001515102,0.0002841185,0.000006780348,0.9891507,0.00007747381,0.001822888,0.00005625506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968374,0.00125617,0.0002260265,0.0005207444,0.00002423098,0.0009561879,0.00002397809,0.00001554468,0.0001397391],"genre_scores_gemma":[0.9991851,0.00006678901,0.0003421423,0.000006480484,0.00009062276,0.00007118723,0.00004923507,0.00001032553,0.0001781525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008769704,"threshold_uncertainty_score":0.230841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294383633078828,"score_gpt":0.2427230993868711,"score_spread":0.2297792630560828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}