{"id":"W2131482458","doi":"10.1093/jnci/djr484","title":"Economic Evaluation of Genomic Test–Directed Chemotherapy for Early-Stage Lymph Node–Positive Breast Cancer","year":2011,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University College London Hospitals NHS Foundation Trust; National Institute for Health and Care Research","keywords":"Medicine; Oncology; Breast cancer; Internal medicine; Lymph node; Stage (stratigraphy); Chemotherapy; Cohort; Cost-effectiveness analysis; Estrogen receptor; Cost effectiveness; Cancer; Gynecology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003450827,0.0001378113,0.0001879817,0.00005727579,0.0000985345,0.000008299724,0.0002455845,0.00006874464,0.00009438932],"category_scores_gemma":[0.00005550062,0.0001033162,0.0001871501,0.00005603059,0.0001250453,0.00002416207,0.00004030612,0.00005469904,0.000001054989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007168222,"about_ca_system_score_gemma":0.001375171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006183883,"about_ca_topic_score_gemma":0.0003856628,"domain_scores_codex":[0.9990292,0.00003809296,0.0003265245,0.0001578158,0.0003219652,0.000126447],"domain_scores_gemma":[0.9979887,0.00002264657,0.0005829543,0.0001019537,0.001266746,0.00003698681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006701077,0.0008755623,0.6217836,0.0001168051,0.006388038,0.000001577914,0.002146829,0.02926166,0.2913613,0.0005619248,0.01027858,0.03052313],"study_design_scores_gemma":[0.003272026,0.00005476127,0.9125735,0.00006496997,0.0002374655,0.00002895413,0.00001771013,0.0002395403,0.08166233,0.0002568298,0.001462509,0.0001294236],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945822,0.001033127,0.00008401203,0.0007768243,0.001145897,0.0002908826,0.001497319,0.000003447779,0.0005863432],"genre_scores_gemma":[0.997531,0.0004647779,0.000491837,0.0003377045,0.0009452642,0.00008315807,0.00001320811,0.00001758234,0.0001154893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.29079,"threshold_uncertainty_score":0.4213111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04436857728916033,"score_gpt":0.3235478128828358,"score_spread":0.2791792355936755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}