{"id":"W2131482458","doi":"10.1093/jnci/djr484","title":"Economic Evaluation of Genomic Test–Directed Chemotherapy for Early-Stage Lymph Node–Positive Breast Cancer","year":2011,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University College London Hospitals NHS Foundation Trust; National Institute for Health and Care Research","keywords":"Medicine; Oncology; Breast cancer; Internal medicine; Lymph node; Stage (stratigraphy); Chemotherapy; Cohort; Cost-effectiveness analysis; Estrogen receptor; Cost effectiveness; Cancer; Gynecology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01054702,0.001127788,0.001270421,0.00140288,0.0003003193,0.001699005,0.001028614,0.001268961,0.003881566],"category_scores_gemma":[0.04142575,0.0005210261,0.002677799,0.00124632,0.0007983635,0.001250539,0.001041046,0.001509817,0.0001537285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009413279,"about_ca_system_score_gemma":0.004248912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00925076,"about_ca_topic_score_gemma":0.004874682,"domain_scores_codex":[0.9899887,0.008724767,0.0002017367,0.0001939694,0.0005785204,0.0003123114],"domain_scores_gemma":[0.9834658,0.01410478,0.001083205,0.0002381396,0.000640742,0.0004674048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.01844631,0.0009936637,0.008459447,0.001795856,0.002155771,0.0004109884,0.00008005799,0.9133473,0.0006588334,0.00822515,0.001419247,0.04400733],"study_design_scores_gemma":[0.005735612,0.01247023,0.01523397,0.001253098,0.004248192,0.0005999207,0.0002879901,0.939281,0.001594883,0.01419138,0.004953046,0.0001507282],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148962,0.01851336,0.03383865,0.004564238,0.0002615142,0.003625769,0.002633647,0.00008284147,0.02158369],"genre_scores_gemma":[0.9940377,0.001399323,0.003048668,0.0001665586,0.00001858041,0.0004443061,0.0003021482,0.000008531219,0.0005741346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01054702,"threshold_uncertainty_score":0.0682984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04436857728916033,"score_gpt":0.3235478128828358,"score_spread":0.2791792355936755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}