{"id":"W2131491275","doi":"10.1091/mbc.e04-12-1096","title":"Visualization of Vacuolar Acidification-induced Transcription of Genes of Pathogens inside Macrophages","year":2005,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of British Columbia; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Vacuole; Biology; Salmonella enterica; Divalent; Biophysics; Efflux; Cell biology; Transcription (linguistics); Regulon; Microbiology; Transcription factor; Biochemistry; Chemistry; Gene; Escherichia coli; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010417,0.000160106,0.0001113013,0.0002239461,0.0001600933,0.0001955658,0.0001798568,0.000293651,0.00116065],"category_scores_gemma":[0.00009021885,0.0001239971,0.0001291031,0.0001102475,0.0001764239,0.0001549531,0.0002312871,0.0004409714,0.0003976025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001870449,"about_ca_system_score_gemma":0.000114045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001983979,"about_ca_topic_score_gemma":0.000260448,"domain_scores_codex":[0.9999475,0.000009681693,0.0000027475,0.00001475087,0.00001076569,0.00001451905],"domain_scores_gemma":[0.9999304,0.00002232012,0.0000107834,0.000009079855,0.00001237446,0.00001510513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001974045,0.000002281441,0.00006603045,0.00001433629,7.337377e-7,0.00002779619,0.00001111068,0.00001120731,0.999495,0.00006942512,0.000009906434,0.0002723095],"study_design_scores_gemma":[0.00001260195,0.00007717696,0.004810238,0.00001114116,0.000005393858,0.000512945,0.00006839697,0.001026267,0.9908765,0.0001900443,0.002404923,0.000004348586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732841,0.001288767,0.02210575,0.0002198789,0.00003085787,0.00004180456,0.0004159352,0.0001337265,0.002479209],"genre_scores_gemma":[0.9569027,0.001337872,0.03637147,0.0001630323,0.00002778201,0.0001486927,0.0005510785,0.00007049313,0.004426918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00116065,"threshold_uncertainty_score":0.003882766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308611998990791,"score_gpt":0.2817068658540615,"score_spread":0.2686207458641536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}