{"id":"W2131498592","doi":"10.1261/rna.044578.114","title":"The folding of 5′-UTR human G-quadruplexes possessing a long central loop","year":2014,"lang":"en","type":"article","venue":"RNA","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Biology; G-quadruplex; RNA; Untranslated region; Computational biology; Nucleic acid structure; Translation (biology); DNA; Loop (graph theory); Three prime untranslated region; Transcriptome; Folding (DSP implementation); Cell biology; Messenger RNA; Gene; Genetics; Molecular biology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228981,0.0002130092,0.0002530579,0.0002145804,0.0002244025,0.0002698754,0.00009436367,0.0002608548,0.000863591],"category_scores_gemma":[0.0003058515,0.0001167154,0.0004109663,0.00025893,0.0001350525,0.0001296876,0.0001245572,0.0002436323,0.0005952292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868805,"about_ca_system_score_gemma":0.000207088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003436006,"about_ca_topic_score_gemma":0.0004032156,"domain_scores_codex":[0.9999005,0.00001582339,0.000009544513,0.00003263764,0.00002405526,0.00001742524],"domain_scores_gemma":[0.9998566,0.00003596233,0.00003881035,0.00001615169,0.00002487468,0.00002754516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000262916,0.00001679138,0.003830043,0.0001197819,0.00001074069,0.0001605657,0.00006004967,0.0004316531,0.9881756,0.0001562599,0.0001588758,0.006616661],"study_design_scores_gemma":[0.00002668481,0.001096177,0.09820975,0.00004636805,0.0001258821,0.001714418,0.0002192678,0.009130137,0.874456,0.0005494993,0.01438381,0.0000419191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912751,0.001032675,0.005058045,0.00005849096,0.00001716068,0.00002934588,0.001559069,0.0001351256,0.0008349649],"genre_scores_gemma":[0.9778565,0.0006214178,0.0125418,0.0000918533,0.00001823105,0.00003477349,0.006742297,0.00003465557,0.002058631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000863591,"threshold_uncertainty_score":0.002888978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006066741334171594,"score_gpt":0.2456343189888366,"score_spread":0.239567577654665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}