{"id":"W2131507856","doi":"10.1523/jneurosci.4426-03.2004","title":"Locus Ceruleus Activation Initiates Delayed Synaptic Potentiation of Perforant Path Input to the Dentate Gyrus in Awake Rats: A Novel β-Adrenergic- and Protein Synthesis-Dependent Mammalian Plasticity Mechanism","year":2004,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Long-term potentiation; Perforant path; Dentate gyrus; Synaptic plasticity; Neuroscience; Locus Ceruleus; Perforant Pathway; Excitatory postsynaptic potential; Chemistry; Internal medicine; Hippocampus; Biology; Medicine; Receptor; Inhibitory postsynaptic potential; Dopamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009356776,0.000224927,0.0003256118,0.0005789084,0.0003533061,0.0001605054,0.0009197588,0.00006304428,0.000006551012],"category_scores_gemma":[0.003188113,0.0001604538,0.0000736422,0.001252194,0.0003720631,0.0008717212,0.00025755,0.0005707023,0.000003779292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001064558,"about_ca_system_score_gemma":0.0003339962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004135995,"about_ca_topic_score_gemma":0.00001544397,"domain_scores_codex":[0.9965767,0.0003648897,0.0007696878,0.0005534976,0.001209441,0.0005257891],"domain_scores_gemma":[0.9983803,0.000417137,0.0006193083,0.0001965739,0.0001567591,0.0002299063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002385295,0.000340502,0.000242824,0.0000182821,0.000001698094,0.0002786736,0.0002685422,0.006911056,0.9910061,0.0003667986,0.000001710648,0.0003252897],"study_design_scores_gemma":[0.0008060104,0.001049139,0.007508296,0.00009932711,0.00001772714,0.0006151818,0.00009508795,0.002975337,0.9863364,0.0003414769,0.00001027033,0.0001457831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927282,0.000008338618,0.004520012,0.001719445,0.0004080799,0.0005739891,0.00001836467,0.000012205,0.00001133171],"genre_scores_gemma":[0.9986612,0.00008293167,0.00009260575,0.001052162,0.00004304232,0.00003122481,5.254176e-8,0.00001831901,0.00001846232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007265471,"threshold_uncertainty_score":0.6543114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04164397221113783,"score_gpt":0.2942041609114449,"score_spread":0.2525601887003071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}