{"id":"W2131509307","doi":"10.1093/ije/dys020","title":"Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles","year":2012,"lang":"en","type":"article","venue":"International Journal of Epidemiology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Economic and Social Research Council; Medical Research Council","keywords":"DNA methylation; Methylation; Endocrinology; Internal medicine; Cholesterol; Insulin resistance; Biology; High-density lipoprotein; Insulin; Medicine; Genetics; DNA; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002625415,0.0002238505,0.0002407094,0.0003596357,0.0001274155,0.0003390858,0.0001767873,0.0002819835,0.001867196],"category_scores_gemma":[0.0009197053,0.000153976,0.0001674535,0.0003439872,0.0001738176,0.0001214852,0.000161533,0.0003432781,0.0002266564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001387931,"about_ca_system_score_gemma":0.00008086571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001738633,"about_ca_topic_score_gemma":0.001879726,"domain_scores_codex":[0.9998493,0.00003382741,0.00001011934,0.0000629881,0.00002492058,0.00001885917],"domain_scores_gemma":[0.9993598,0.0001314116,0.000310543,0.00005598878,0.00007058509,0.00007171668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001163487,0.00003798673,0.957182,0.00004239092,0.0002353961,0.0001084799,0.0001189103,0.0001377099,0.03295849,0.00003688519,0.0001775381,0.007800792],"study_design_scores_gemma":[0.000006822005,0.00009603185,0.9973895,0.000004083333,0.00005620195,0.0003053044,0.00002702737,0.0002038409,0.001676732,0.0000498011,0.0001814662,0.000003262028],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998062,0.0006095251,0.0005802086,0.0000374064,0.000004591132,0.000004394681,0.0003731973,0.00001538251,0.0003132899],"genre_scores_gemma":[0.9988095,0.0001538418,0.0003296189,0.00001572021,0.000006123802,0.000004336139,0.0003117163,0.000004651213,0.0003646402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001867196,"threshold_uncertainty_score":0.006246448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02948341425382001,"score_gpt":0.3316854410612647,"score_spread":0.3022020268074447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}