{"id":"W2131530904","doi":"10.1158/0008-5472.can-05-2103","title":"A Novel RING-Type Ubiquitin Ligase <i>Breast Cancer-Associated Gene 2</i> Correlates with Outcome in Invasive Breast Cancer","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto; Canadian Institutes of Health Research","funders":"","keywords":"Ubiquitin ligase; Breast cancer; Cancer research; DNA ligase; Cancer; Ubiquitin; Estrogen receptor; RING finger domain; Biology; Chemistry; Molecular biology; Gene; Genetics; Transcription factor; Zinc finger","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007087017,0.0003191459,0.0003525277,0.0001813099,0.0002139075,0.0000768243,0.0004987631,0.0003008064,0.0004974467],"category_scores_gemma":[0.0001050252,0.0002815019,0.0000786686,0.0007552805,0.0002729987,0.00002072404,0.000296806,0.0007076238,0.00003544493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005381563,"about_ca_system_score_gemma":0.001483194,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.007535478,"about_ca_topic_score_gemma":0.03570365,"domain_scores_codex":[0.9970817,0.000166807,0.0003763801,0.0007597306,0.0005478858,0.001067523],"domain_scores_gemma":[0.9983322,0.00005944123,0.0001347766,0.0004419176,0.0007342951,0.000297343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009986596,0.0002689714,0.1837345,0.00007974412,0.0001360938,0.00002845055,0.0002399593,0.001034055,0.807415,0.0000258141,0.001682959,0.004355761],"study_design_scores_gemma":[0.004018705,0.0003730436,0.06693765,0.0005909905,0.00003726899,0.0001298581,0.0002000754,0.0001692669,0.922431,0.00001818763,0.004377155,0.000716827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990803,0.003623138,0.00001030384,0.002799419,0.0001549507,0.0006669685,0.001410391,0.00003073654,0.0005010696],"genre_scores_gemma":[0.9929739,0.002735253,0.00008403906,0.0007188839,0.0007670007,0.0008115111,0.0001119271,0.00008449774,0.001712939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1167969,"threshold_uncertainty_score":0.9999637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04781845951193837,"score_gpt":0.3451737958389187,"score_spread":0.2973553363269803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}