{"id":"W2131575812","doi":"10.1021/bi0473760","title":"Effect of Arginine Loss in Myelin Basic Protein, as Occurs in Its Deiminated Charge Isoform, on Mediation of Actin Polymerization and Actin Binding to a Lipid Membrane in Vitro","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Actin; Chemistry; Biophysics; Lipid bilayer; Actin-binding protein; Biochemistry; Gene isoform; Calmodulin; Arginine; Myelin basic protein; Myelin; Membrane; Actin cytoskeleton; Cytoskeleton; Biology; Amino acid; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004731182,0.0001507676,0.0002275071,0.000193569,0.00001397036,0.000006553852,0.0001145089,0.0001902396,0.00001231156],"category_scores_gemma":[0.0007586296,0.0001490479,0.00003127895,0.0003365251,0.00002992072,0.000009333176,0.0000554764,0.0001397793,0.000002962653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005204731,"about_ca_system_score_gemma":0.00007601648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006036794,"about_ca_topic_score_gemma":0.00002201968,"domain_scores_codex":[0.9988695,0.00007367369,0.0003158646,0.0003020405,0.0001723302,0.00026656],"domain_scores_gemma":[0.9995557,0.00004077153,0.0001227188,0.000165246,0.00003415234,0.0000814221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001844221,0.00009252519,0.002580832,0.0002616602,0.000007327776,0.000003929129,0.00006665762,0.00002567697,0.9882873,8.996698e-7,0.000005856599,0.006823079],"study_design_scores_gemma":[0.001530972,0.0003971207,0.0009567463,0.0001896036,0.000002588096,0.000003536292,0.00003797634,0.0004225645,0.9963148,1.679228e-7,0.00002134232,0.0001225606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990742,0.0001354627,0.000004473436,0.0002227576,0.00001460004,0.000430018,0.00002390714,0.000004007648,0.00009057757],"genre_scores_gemma":[0.9993708,0.00006735861,0.00004404755,0.00002432143,0.00006590046,0.00005847933,0.0001569397,0.0000149835,0.0001972385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008027486,"threshold_uncertainty_score":0.6077998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004929061921241398,"score_gpt":0.2669965255245769,"score_spread":0.2620674636033355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}