{"id":"W2131575812","doi":"10.1021/bi0473760","title":"Effect of Arginine Loss in Myelin Basic Protein, as Occurs in Its Deiminated Charge Isoform, on Mediation of Actin Polymerization and Actin Binding to a Lipid Membrane in Vitro","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Actin; Chemistry; Biophysics; Lipid bilayer; Actin-binding protein; Biochemistry; Gene isoform; Calmodulin; Arginine; Myelin basic protein; Myelin; Membrane; Actin cytoskeleton; Cytoskeleton; Biology; Amino acid; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002850159,0.0003835939,0.0002074621,0.00009363655,0.00008515456,0.0002467873,0.000323558,0.0003045953,0.0007721559],"category_scores_gemma":[0.0003694537,0.0001499868,0.0001490768,0.0001070746,0.0003285391,0.0001938747,0.0001465749,0.0004778399,0.0002154581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000248051,"about_ca_system_score_gemma":0.000131763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006940819,"about_ca_topic_score_gemma":0.0005495879,"domain_scores_codex":[0.9996746,0.000108795,0.00004510546,0.00006298605,0.00005425492,0.00005439688],"domain_scores_gemma":[0.9995176,0.0001638946,0.0001420945,0.00005295321,0.00003435241,0.00008918763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009897128,0.0001248761,0.0002693671,0.00003125453,0.00001047259,0.00007991994,0.00001768412,0.00008960695,0.9978435,0.00003534274,0.00001551834,0.0004927737],"study_design_scores_gemma":[0.00006394037,0.002509728,0.005065191,0.00000514537,0.00002331053,0.0003279407,0.00002645188,0.000932388,0.9899862,0.0000209962,0.001029692,0.000008882961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993342,0.0002904983,0.0001227914,0.00001700948,0.000008906396,0.000006818132,0.00004028159,0.000007214546,0.0001722617],"genre_scores_gemma":[0.9983395,0.0002677778,0.0005157911,0.00003613263,0.000009317813,0.00001185902,0.0002649579,0.00001203534,0.0005426927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007721559,"threshold_uncertainty_score":0.002583086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004929061921241398,"score_gpt":0.2669965255245769,"score_spread":0.2620674636033355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}