{"id":"W2131585334","doi":"10.1046/j.1462-5822.2003.00254.x","title":"Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity","year":2003,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biology; Crypt; Toxicity; Cell biology; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004239428,0.0001286071,0.0001848689,0.0001322164,0.00004736978,0.00000803895,0.0001116436,0.0001270694,0.000006631929],"category_scores_gemma":[0.0007351016,0.0001283465,0.0000291064,0.0002362055,0.00009765001,0.000002974406,0.0001510672,0.00007508578,0.00001183987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003066005,"about_ca_system_score_gemma":0.00005268065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002484435,"about_ca_topic_score_gemma":0.0001138662,"domain_scores_codex":[0.9988334,0.0002085599,0.0002771228,0.0003684484,0.00004090836,0.0002715755],"domain_scores_gemma":[0.9995386,0.00003885557,0.0000651973,0.0001829699,0.00009827896,0.00007612315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001675111,0.00004727591,0.001860271,0.0000235693,0.00001334979,0.000002622367,0.0001807962,0.0002556896,0.9968793,0.00007029421,0.0003216499,0.0001776658],"study_design_scores_gemma":[0.0005526256,0.000464757,0.0004119156,0.0000237063,0.000003954086,0.000005304781,0.000101928,0.00002392593,0.9874202,0.00002205073,0.01084403,0.0001256149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918547,0.0001672395,0.007141932,0.00009229806,0.00008308412,0.0004140761,0.00004785563,0.000005170383,0.000193604],"genre_scores_gemma":[0.9967719,0.00005115979,0.002739366,0.0001331667,0.00003082725,0.00002503808,0.00007607494,0.00001184457,0.0001605693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01052238,"threshold_uncertainty_score":0.5233817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078841565523122,"score_gpt":0.2515795176228324,"score_spread":0.2407911019676011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}