{"id":"W2131608481","doi":"10.4049/jimmunol.1001480","title":"CD8 Controls T Cell Cross-Reactivity","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Wellcome Trust","keywords":"T-cell receptor; Repertoire; T cell; Biology; CD8; Receptor; Cross-reactivity; Cell biology; Antigen; Major histocompatibility complex; Reactivity (psychology); Immunology; Cell; Immune system; Genetics; Cross reactions; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001488554,0.0003046356,0.0001803287,0.0002005426,0.0002199729,0.0004910076,0.0003237783,0.0003118452,0.002089035],"category_scores_gemma":[0.0002484361,0.0001148747,0.0001136629,0.00007854417,0.0002645895,0.0002508615,0.0005003251,0.0005609521,0.0007505678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003672118,"about_ca_system_score_gemma":0.0001908461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002505673,"about_ca_topic_score_gemma":0.0003495292,"domain_scores_codex":[0.9997172,0.00004288754,0.0000136527,0.0000673177,0.00003382301,0.0001251052],"domain_scores_gemma":[0.9998578,0.00002738588,0.00002745013,0.00002349343,0.00002147258,0.00004245899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009512877,0.00003182861,0.0007332655,0.00002620971,0.000002125505,0.0001219536,0.00003688917,0.0001640433,0.9895207,0.0004884727,0.00007154475,0.008707942],"study_design_scores_gemma":[0.00006591075,0.0004813788,0.006762782,0.00002335738,0.00001362268,0.001024349,0.00009034856,0.005041682,0.9777474,0.0007851461,0.007955004,0.000009040419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920316,0.001468171,0.002429631,0.0000756782,0.00002616641,0.00001685009,0.00002735068,0.0001209286,0.00380369],"genre_scores_gemma":[0.9980403,0.0002359255,0.0007130895,0.00002294562,0.00001027998,0.000009159906,0.00002152411,0.00001085554,0.0009360919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002089035,"threshold_uncertainty_score":0.006988466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008591026481641994,"score_gpt":0.2372971458438313,"score_spread":0.2287061193621893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}