{"id":"W2131608481","doi":"10.4049/jimmunol.1001480","title":"CD8 Controls T Cell Cross-Reactivity","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Wellcome Trust","keywords":"T-cell receptor; Repertoire; T cell; Biology; CD8; Receptor; Cross-reactivity; Cell biology; Antigen; Major histocompatibility complex; Reactivity (psychology); Immunology; Cell; Immune system; Genetics; Cross reactions; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00147139,0.0003020647,0.000671222,0.0001978896,0.0005026372,0.0000278832,0.001265911,0.0006784355,0.001648795],"category_scores_gemma":[0.0003511686,0.0001878628,0.000288807,0.0001544051,0.001625108,0.0002259067,0.0002224656,0.002845153,0.001153785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003485986,"about_ca_system_score_gemma":0.0002002405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001144244,"about_ca_topic_score_gemma":0.00007309097,"domain_scores_codex":[0.9975458,0.0007163686,0.0008207274,0.0001897621,0.00006360644,0.0006637723],"domain_scores_gemma":[0.9966183,0.001326122,0.0009788461,0.0006934949,0.0003525298,0.00003066702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00128031,0.0003727548,0.001310875,0.000005486835,0.0003991846,0.00002145649,0.0003821924,0.000004690603,0.9919187,0.000601613,0.001071858,0.002630814],"study_design_scores_gemma":[0.00409257,0.0008394233,0.005054221,0.000009721807,0.0001424577,0.003972863,0.0002828983,8.351709e-7,0.8711769,0.0006458839,0.1135766,0.0002055632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816144,0.006792829,0.0001412923,0.000904497,0.006281978,0.0001720834,0.00001012691,0.00003995452,0.004042834],"genre_scores_gemma":[0.9948638,0.0005302501,0.00006171891,0.0002557838,0.0001718407,0.000004218269,0.000006223343,0.00002878705,0.004077388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1207418,"threshold_uncertainty_score":0.999624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008591026481641994,"score_gpt":0.2372971458438313,"score_spread":0.2287061193621893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}