{"id":"W2131731945","doi":"10.4049/jimmunol.1000089","title":"Reporter Alleles that Inform on Differences in Cre Recombinase Expression","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Leukemia and Lymphoma Society; Sandler Foundation; University of California, San Francisco","keywords":"Cre recombinase; Allele; Biology; Recombinase; Genetics; Reporter gene; Gene; Gene expression; Recombination; Transgene; Genetically modified mouse","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009566917,0.0008381779,0.0006284398,0.0006688011,0.0002636319,0.0007734438,0.0009453119,0.001567233,0.003002063],"category_scores_gemma":[0.001050997,0.0005271799,0.0005745547,0.0003738592,0.0007793947,0.0008249879,0.0007773967,0.002397713,0.001238841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003526934,"about_ca_system_score_gemma":0.0005143358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002018406,"about_ca_topic_score_gemma":0.0004926635,"domain_scores_codex":[0.9991707,0.0001180418,0.0001011953,0.0001950673,0.0002780505,0.0001370568],"domain_scores_gemma":[0.9988984,0.0003254288,0.0003480481,0.0001737459,0.0001061196,0.0001482427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005659862,0.00003073735,0.00009370969,0.00003432759,0.000003872301,0.00006204303,0.00002304638,0.00006084741,0.996105,0.000796262,0.00006177946,0.002671743],"study_design_scores_gemma":[0.00005468711,0.0001304306,0.0008699566,0.00001685752,0.00002191189,0.0009151837,0.00002870611,0.0005238404,0.9893619,0.0002905013,0.007768123,0.00001781958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5428981,0.002753106,0.4394427,0.001243361,0.0005491783,0.0007094785,0.00170537,0.001813929,0.008884818],"genre_scores_gemma":[0.7776808,0.003165702,0.2008029,0.0005944053,0.0001225035,0.0007562308,0.003157185,0.0006596688,0.01306072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003002063,"threshold_uncertainty_score":0.01004297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01677181706636603,"score_gpt":0.2461673120263924,"score_spread":0.2293954949600264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}